Articles Vol. 63 No. chuyên đề 2-HN Y học Giới tính (2022) 18/11/2022

SPERM COLLECTION BY MICRO TESE METHOD IN PATIENTS WITH NONOBSTRUCTIVE AZOOSPERMIA AND SOME RELATED FACTORS

Quach Thi Yen1,2, Trinh Quoc Thanh3,4, Doan Minh Thuy1,2, Vu Thi Hao5,6, Nguyen Huyen Trang1,2, Hoang Phuc Toan1,2, Ha Quy Anh1,2
1 Vietnam University of Traditional Medicine
2 Học viện Y Dược học Cổ truyền Việt Nam
3 Vietnam Military Medical University
4 Học viện Quân y
5 Thai Nguyen University of Medicine and Pharmacy
6 Đại học Y Dược Thái Nguyên
Corresponding author: doanminhthuyvn@yahoo.com
DOI: 10.52163/yhc.v63i7.494
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Keywords
Microdissection testicular sperm extraction (micro tese); Non-obstructive azoospermia; sperm collection.
Abstract

Question: Microdissection testicular sperm extraction (micro tese) is a highly effective
method of sperm collection with a low risk of secondary testicular damage. Objectives: To
evaluate the sperm collection rate by microtese method in patients with nonobstructive
azoospermia (NOA) and some related factors. Subjects and research methods: 132
NOA patients were micro-tese made at the Military Clinical Embryo Institute - Vietnam
Military Medical University from 5/2017 to 12/2019. Results: The sperm collection
rate was 40.15%. There was no association between age, BMI, duration of infertility,
AZF with sperm collection rate. There was a relationship between testicular volume,
hormone concentration, histopathology, and sperm collection rate. The cut-off point of
the right and left testicular volumes were 5.5mL, with a sensitivity of 86.3% and 84.3%,
specificity of 50.6% and 51.9%, and a curve area of 0.707, respectively and 0.676 (p <
0.001 and p < 0.01). The cut-off points of FSH, LH and testosterone were 13.41mIU/
mL, 7.64mIU/mL and 3.02ng/mL, respectively, with a sensitivity of 74.4%; 69.9%;
86.8%, specificity 58.5%; 56.6%; 46.8% and the corresponding curve area was 0.666;
0.625; 0.647. Conclusion: Although the relationship between testicular volume, FSH,
LH, testosterone levels, and histopathology with microtese sperm collection rate in NOA
patients was found, the prognostic value was low.

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