Articles Vol. 67 No. CĐ4-HN Ký sinh trùng-HN Hóa sinh 2026 21/04/2026

ASSOCIATION BETWEEN SIC AND DIC SCORES IN SEPTIC SHOCK PATIENTS

Phan Vu Anh Minh1,2, Pham Thi Tuoi1,2, Doan Xuan An1,2, Nguyen Thanh Tri1,2, Nguyen Di Linh1,2, Bui Thi Diem Kieu1,2, Tran Thuy Anh1,2
1 Univesity Medical Center in Ho Chi Minh City
2 Bệnh viện Đại học Y Dược thành phố Hồ Chí Minh
DOI: 10.52163/yhc.v67iCD4.4857
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Keywords
Septic shock, septic induced coagulopathy, disseminated intravascular coagulation.
Abstract

Objective: To evaluate the relationship between the SIC score and DIC score in patients with septic shock at University Medical Center Ho Chi Minh City.

Methods: A prospective follow-up study was conducted on 47 newly diagnosed septic shock patients admitted to the Intensive Care Unit between June 2023 and June 2024.

Results: The mean age was 69.77 ± 14.54 years, with a male-to-female ratio of 0.8/1. Patients aged ≥ 60 years had a significantly higher prevalence of comorbidities compared to younger patients. The prevalence of patients with SIC was 65.96%, and with DIC was 29.79%. Overt DIC occurred only in patients who met the SIC criteria, with a statistically significant association (p = 0.001). Thrombocytopenia, decreased fibrinogen, elevated D-dimer, and fibrin monomer were strongly associated with overt DIC, whereas INR had limited value.

Conclusion: The SIC score enables early recognition of sepsis-induced coagulopathy and predicts progression to overt DIC, supporting timely risk stratification and clinical management.

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