Articles Vol. 67 No. CĐ2-NCKH 05/03/2026

HIGH-SENSITIVITY TROPONIN I CONCENTRATIONS IN TYPE 2 DIABETES PATIENTS: ASSOCIATION WITH AGE AND GENDER

Quoc Ky Duyen1,2, Do Anh Duong1,2, Nguyen Van Chinh3,4
1 Faculty of Medical Laboratory Technology, Nguyen Tat Thanh University
2 Khoa Kỹ thuật Xét nghiệm Y học, Trường Đại học Nguyễn Tất Thành
3 Long Thanh regional General Hospital
4 Bệnh viện Đa khoa khu vực Long Thành
DOI: 10.52163/yhc.v67iCD2.4466
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Keywords
Type 2 diabetes, hs-TnI, cardiovascular risk.
Abstract

Objective: This study was conducted to describe the distribution characteristics of high-sensitivity troponin I levels according to age and sex in two groups of patients with and without type 2 diabetes, thereby assessing the role of high-sensitivity troponin I in early cardiovascular complication screening and prognosis.

Methods: A case-control study was conducted on 372 patients aged ≥ 18 years who visited or were admitted to Long Thanh regional General Hospital from December 2024 to June 2025, including 183 patients with type 2 diabetes and 189 patients without type 2 diabetes. Patients with a history of or current cardiovascular disease were excluded.

Results: The study showed that high-sensitivity troponin I levels were significantly higher in the type 2 diabetes group compared to the non-type 2 diabetes group. The differences were statistically significant with respect to age and sex.

Conclusion: Measurement of high-sensitivity troponin I is useful for early detection of cardiovascular risk in type 2 diabetes patients, even before clinical manifestations appear. However, high-sensitivity troponin I thresholds should be adjusted according to age and sex when assessing cardiovascular risk.

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