Articles Vol. 67 No. CĐ2-NCKH 05/03/2026

CHARACTERISTICS OF AFLATOXIN CONTAMINATION IN MEDICINAL PLANTS AT NGHE AN TRADITIONAL MEDICINE HOSPITAL IN 2023

Ho Van Thang1,2, Nguyen Thi Kim Dinh3,4, Nguyen Thi Nga2,3, Duong Dinh Chinh3,4, Cao Ba Loi5,6
1 Nghe An Traditional Medicine Hospital
2 Bệnh viện Y học cổ truyền Nghệ An
3 Nghe An Department of Health
4 Sở Y tế tỉnh Nghệ An
5 National Institute of Malariology Parasitology and Entomology
6 Viện Sốt rét Ký sinh trùng Côn trùng Trung ương
DOI: 10.52163/yhc.v67iCD2.4432
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Keywords
Medicinal plants, fungus, aflatoxin.
Abstract

Objective: To determine the prevalence and some related factors of aflatoxin contamination in traditional herbal medicines at Nghe An Traditional Medicine Hospital in 2023.

Subjects and methods: A sample size of 170 traditional herbal medicines included in the list of medicines covered by insurance was used. The study was a descriptive experimental design conducted in the laboratory using high-performance liquid chromatography for qualitative and quantitative determination of aflatoxin.

Results: The overall aflatoxin contamination rate was 16/170, with 9 samples contaminated with one type of aflatoxin, 5 samples contaminated with two types of aflatoxin, and 2 samples contaminated with three types of aflatoxin. There were 25 instances of aflatoxin contamination (14.41%), with the highest rate of aflatoxin B2 contamination (48%), followed by aflatoxin G1 at 24%, aflatoxin B1 at 16%, and the lowest rate of aflatoxin G2 at 12%. The aflatoxin contamination rate in traditional medicine samples contaminated with mold was 19.64%, while in samples not contaminated with mold it was 4.39%. The aflatoxin contamination rate in traditional Chinese medicine (15.73%) was higher than in traditional Vietnamese medicine (2.47%).

Conclusion: Aflatoxin contamination in traditional medicine products is cumulative over time due to mold contamination. Therefore, a model for assessing health risks from aflatoxin exposure is needed.

References
[1]
Mina Nan, Huali Xue, Yang Bi. Contamination detection and control of mycotoxins in fruits and vegetables. Toxins (Basel), 2022, 14 (5): 309. doi: 10.3390/toxins14050309. Google Scholar
[2]
Viện Công nghệ thực phẩm. Ô nhiễm độc tố nấm mốc Ergot alkaloids trong các sản phẩm ngũ cốc và chiến lược kiểm soát (tài liệu dịch từ Fri Admin), 2023. https://firi.vn./2023/05/23/author.caobach. Google Scholar
[3]
Cardoma T.D, Hangantileke S.G, Noomhorm A. Aflatoxin research on grain in Asia - its problems and possible solutions. FAO, 2013. https://www.fao.org/4/x5036e/x5036e1e.htm Google Scholar
[4]
Viện Sốt rét Ký sinh trùng Côn trùng Trung ương. Phương pháp nghiên cứu khoa học (Giáo trình giảng dạy sau đại học). Nhà xuất bản Y học, Hà Nội, 2023. Google Scholar
[5]
Bộ Y tế. Quy chuẩn kỹ thuật quốc gia đối với giới hạn ô nhiễm độc tố vi nấm trong thực phẩm: QCVN 8-1:2011/BYT, 2011. Google Scholar
[6]
Shabeer S, Asad S, Jamal A, Ali A. Aflatoxin contamination, its impact and management strategies: an updated review. The Toxins, 2022, 14: 307. doi: 10.3390/toxins14050307. Google Scholar
[7]
Nguyễn Ngọc Kim Vy. Aflatoxin - Độc tố nguy hiểm gây ung thư gan. Tạp chí Khoa học và Công nghệ, 2019, 12: 51-52. Google Scholar
[8]
Özer H, Kaplan F. Determination of aflatoxin b1 and total aflatoxin (B1, B2, G1, and G2) risk in pistachios and dried figs collected from local markets in Şanlıurfa by high performance liquid chromatography method. ISPEC Journal of Agricultural Sciences, 2025, 9 (3): 655-666. doi: 10.5281/zenodo.15782004. Google Scholar