Articles Vol. 63 No. 5 (2022) 29/09/2022

THE EFFECT OF HYPERBARIC OXYGEN THERAPY IN TREATING FOR IRRADIATED HEAD AND NECK CANCER PATIENTS: A SYSTEMATIC REVIEW

Do Thi Thu Hien1,2, Vu Manh Tuan3,4, Ngo Van Toan3,4
1 School of Dentistry
2 Viện Đào tạo Răng Hàm Mặt
3 Hanoi Medical University
4 Trường Đại học Y Hà Nội
Corresponding author: catarina.hiendo@gmail.com
DOI: 10.52163/yhc.v63i5.441
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Keywords
Hyperbaric oxygen, head and neck cancer, radiation therapy, systematic review
Abstract

Objectives: To summarize the effectiveness of hyperbaric oxygen therapy in the treatment of patients
who underwent radiation therapy for head and neck cancer from 1992 to 2022.
Subjects and methods: This systematic review uses the open data sources Pubmed, Google Scholar
to search for articles and full-text researches written in English in accordance with the selection
criteria.
Results: The number of articles selected and included in the systematic review was 21. The results
show that hyperbaric oxygen therapy is effective in reducing xerostomia, however, its effectiveness
in reducing risk/accelerating healing process of osteoradionecrosis and improving patients’ quality
of life has not been agreed.
Conclusion: More well-designed randomized controlled trials with uniform protocols are needed to
recommend the use of hyperbaric oxygen therapy for irradiated head and neck cancer patients.

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