Objective: To determine the adherence to the Vietnam Heart Association’s heart failure treatment guidelines at Trưng Vương Hospital.
Methods: A cross-sectional descriptive study was conducted on 119 heart failure with reduced ejection fraction outpatients. Logistic and linear regression analyses were utilized to identify factors associated with left ventricular ejection fraction classification and the total number of foundational medication classes prescribe.
Results: High prescription rates were recorded for foundational classes: renin-angiotensin system inhibitors (92.4%), SGLT2 inhibitors (90.7%), mineralocorticoid receptor antagonists (84.8%), and beta-blockers (82.4%). Notably, 61.3% of patients achieved the “four-pillar” combination therapy. SGLT2 inhibitors achieved an optimal target dose rate of 89,9%. Conversely, target dose achievement for ACEi/ARB/ARNI, beta-blockers, and MRAs remained below 1%. Chronic kidney disease was the only statistically significant barrier reducing the number of combined medication classes (B = -0.670; p < 0.001).
Conclusion: Trung Vuong Hospital has achieved success in implementing early multi-therapy for heart failure patients, highlighting the advantages of SGLT2i in patients with smaller body habitus. However, the low rate of target dose achievement for conventional therapies necessitates individualized titration strategies.