Articles Tập 67 Số CĐ1-NCKH 27/01/2026

MORPHOLOGICAL CHANGES OF THE CERVIX IN PREGNANT WOMEN WITH HIGH RISK OF PRETERM BIRTH BEFORE 34 WEEKS AT HANOI OBSTETRICS & GYNECOLOGY HOSPITAL.

Le Quang Hoa1,2, Mai Trong Hung1,2,3,4, Truong Quang Vinh3,4, Pham Duc Anh3,4, Do Xuan Hai3,4
1 Hanoi Obstetrics and Gynecology Hospital
2 Bệnh viện Phụ Sản Hà Nội
3 University of Medicine and Pharmacy, Vietnam National University, Hanoi
4 Trường Đại học Y Dược, Đại học Quốc gia Hà Nội
DOI: 10.52163/yhc.v67iCD1.4228
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Abstract

Objective: This study aims to describe morphological changes of the cervix using transvaginal ultrasound in high-risk pregnant women and to determine the predictive value of these changes for preterm birth.

Method: A prospective descriptive study was conducted on 182 high-risk pregnant women at Hanoi Obstetrics and Gynecology Hospital from June 2024 to August 2025. A total of 1227 transvaginal ultrasound examinations were performed periodically from week 16 to week 34 of pregnancy. The parameters measured included cervical length, internal os shape (T, Y shapes), functional cervical length, and internal os dilation. The data was statistically analyzed to determine the predictive thresholds for preterm birth.

Results: The rate of preterm birth in the study group was 18.1%. The T-shape cervix accounted for 80.4%, while the Y-shape accounted for 19.6%. The average cervical length was 33.0±3.6 mm and gradually decreased with gestational age. There was a statistically significant difference between the < 34 weeks preterm birth group and the ≥ 34 weeks birth group. In pregnant women with cervical morphological changes (Y-shape), the functional cervical length was significantly shorter. The prognostic value of cervical length for preterm birth varies by gestational age and cervical morphology. Cervical length in T-shaped cervices has low prognostic value. However, functional cervical length in Y-shaped cervices demonstrates high prognostic value at specific gestational ages: at 22-24 weeks, the optimal cutoff is ≤ 33 mm (sensitivity 84.62%, specificity 83.33%); at 25-27 weeks, it is ≤ 28 mm (sensitivity 76.47%, specificity 72.00%); at 28-30 weeks, it is ≤ 26 mm (sensitivity 62.07%, specificity 83.58%); and at 31-34 weeks, it is ≤ 25 mm (sensitivity 85.71%, specificity 54.69%).

Conclusion: Transvaginal ultrasound of cervical morphology is an effective and highly valuable method for predicting the risk of preterm birth in high-risk pregnant women. Cervical morphological change from T shape to Y shape with short functional cervical length is an important early sign, prompting timely and effective interventions.

 

References
[1]
World Health Organization. (2015). Born too soon: the global action report on preterm birth. World Health Organization. Google Scholar
[2]
O’Hara SM, Zelesco MD, Sun Z. Cervical length for predicting preterm birth and a comparison of ultrasonic measurement techniques. Australas J Ultrasound Med. 2013;16(3):124–34. DOI: 10.1002/j.2205-0140.2013.tb00100.x Google Scholar
[3]
Habashy AE, et al. Comparison between static and dynamic cervical assessment in preventing preterm birth. Int J Reprod Contracept Obstet Gynecol. 2022;11(11):2954–62. Google Scholar
[4]
Nguyễn Đình Vũ, Huỳnh Nguyễn Khánh Trang. Vai trò của siêu âm ngả âm đạo đo chiều dài cổ tử cung để tiên lượng sanh non ở bệnh nhân dọa sanh non. TCYHTPHCM. 2012;16(1):270–270. Google Scholar
[5]
Chmait RH, et al. Cervical funneling is more predictive of preterm birth than cervical length alone in nulliparous women. Am J Obstet Gynecol. 2023;228:S722–23. Google Scholar
[6]
Vũ Bá Quyết, Nguyễn Xuân Hợi, Đào Thị Hoa, Đinh Bích Thủy, Nguyễn Thị Huyền Linh. Khảo sát độ dài cổ tử cung ở 3500 thai phụ có tuổi thai từ 19–23 tuần 6 ngày bằng siêu âm qua đường âm đạo.Tạp chí Y học Việt Nam. 2021;501(1). DOI: https://doi.org/10.51298/vmj.v501i1.454 Google Scholar
[7]
Nguyen THT, Vu VT, Nguyen VQH. Distribution of uterocervical angles of pregnant women at 16+0 to 23+6 weeks gestation with low risk for preterm birth: first Vietnamese cohort. BMC Pregnancy Childbirth. 2023;23:301. Google Scholar
[8]
Nguyen TTH, Vu VT, Nguyen VQH. Uterocervical angle and cervical length measurements for spontaneous preterm birth prediction in low-risk singleton pregnant women. Arch Gynecol Obstet. 2024;310:1611–19. DOI: 10.1007/s00404-024-07646-4 Google Scholar