Articles Vol. 63 No. 5 (2022) 29/09/2022

EFFECTIVENESS OF ANALGESIA WITH FENTANYL OR KETAMIN COMBINED MORPHINE OR MORPHIN ON ABDOMINAL SURGERY PATIENTS

Bui Dang Minh Tri1,2, Dinh Thi Thanh Loan3,4, Nguyen Hong Tham5,6, Nguyen Thu Thuy7,8
1 Pham Ngoc Thach Medical University
2 Trường Đại học Y khoa Phạm Ngọc Thạch
3 Tay Do University
4 Trường Đại học Tây Đô
5 Vinh Long General Hospital
6 Bệnh viện Đa khoa Vĩnh Long
7 108 Military Central Hospital
8 Bệnh viện Trung ương Quân đội 108
Corresponding author: drtribui1@gmail.com
DOI: 10.52163/yhc.v63i5.422
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Keywords
Abdominal surgery, fentanyl, morphine, ketamine.
Abstract

Objective: To compare the analgesic efficacy of fentanyl, morphine in combination with ketamine
and morphine alone after abdominal surgery.
Subjects and methods: Prospective clinical, randomized and controlled study on 90 patients
undergoing elective abdominal surgery at Vinh Long General Hospital from June 2021 to June 2022.
Results: The analgesic effectiveness as lying still was similar between the three groups with the
average VAS score at all time points below 3 points. The analgesic effectiveness as moving of the
fentanyl group alone and the morphine-ketamine combination group were better than that of the
morphine alone group at the time of evaluation on day 2. The percentage of patients with pain relief
levels from satisfied or above (all over 90%), A/D ratio (all > 74%) were similar between the three
groups.
Conclusion: The analgesic effectiveness as lying still was similar between the three groups, while
the analgesic effectiveness as moving was better in the fentanyl group and in the morphine-ketamine
combination group than in the morphine alone group (day 2).

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