Articles Vol. 63 No. 5 (2022) 29/09/2022

EFFECTS OF KNEE OSTEOARTHRITIS THERAPY BY PLATELET RICH PLASMA IN VO TRUONG TOAN HOSPITAL

Tran Do Thanh Phong1,2, Nguyen Tuan Canh1,2, Nguyen Tan Loc1,2, Tran Thi Mai Phuong1,2, Mai Nguyet Thu Hong1,2
1 Vo Truong Toan University
2 Trường Đại học Võ Trường Toản
Corresponding author: tdtphong@vttu.edu.vn
DOI: 10.52163/yhc.v63i5.420
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Keywords
Knee osteoarthritis, platelet-rich plasma, PRP.
Abstract

Aim: (1) Evaluation results on VAS and KOOS scores after 12 months of treatment of osteoarthritis
patients with platelet-rich plasma (PRP) therapy; (2) Evaluation results on ultrasonography and MRI
after 12 months of treatment of osteoarthritis patients with platelet-rich plasma (PRP) therapy.
Subject and Method: Intervention study on 40 patients diagnosed with stage 2 and 3 osteoarthritis
according to Kellgren and Lawrence, who were intervened by PRP. Evaluation on clinical, ultrasound
and magnetic resonance after 12 months of follow-up.
Result: VAS score of the patients before the intervention was 6.53±1.81, after 12 months of the
intervention it was 3.93±2.74, KOOS score of the patients before the intervention was 46.27±13, 62,
after 12 months of intervention was 83.09±13.14 (P<0.05). On ultrasound, the average thickness of
articular cartilage of patients before intervention was 1.74±0.39, after 12 months of intervention, it
was 1.83±0.36 with improved cartilage thickness over time (P <0.05), the patient had a reduced rate
of synovial membrane proliferation (P<0.05). On magnetic resonance, after PRP treatment, there
was an improvement in the lesions of the medial condyle of the femur, the outer condyle of the
femur, the patellar surface, the condylar surface and the lateral tibial plateau (P<0.05). Conclusion:
The treatment of knee osteoarthritis with platelet-rich plasma is effective in improving the cartilage
thickness on ultrasound and magnetic resonance, thereby improving the mobility of the knee joint.

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