Articles Vol. 67 No. 1 15/01/2026

FACTORS INFLUENCING MID-TERM OUTCOMES IN PATIENTS WITH CHRONIC INFRAPOPLITEAL ARTERIAL OCCLUSIVE DISEASE TREATED BY BALLOON ANGIOPLASTY AT THE UNIVERSITY MEDICAL CENTER HO CHI MINH CITY

Nguyen Minh Tan1,2,3,4, Lam Thao Cuong1,2,3,4, Nguyen Hoai Nam2,4,5,6
1 Faculty of Thoracic and Vascular Surgery, University Medical Center Ho Chi Minh city
2 Department of Thoracic and Cardiovascular Surgery, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh city
3 Khoa Lồng ngực Mạch máu, Bệnh viện Đại học Y Dược thành phố Hồ Chí Minh
4 Bộ môn Phẫu thuật Lồng ngực Tim mạch, Trường Y, Đại học Y Dược thành phố Hồ Chí Minh
5 Minh Anh International Hospital
6 Bệnh viện Quốc tế Minh Anh
DOI: 10.52163/yhc.v67i1.4154
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Keywords
Infrapopliteal arterial occlusive disease, amputation, mortality, BMI, eGFR.
Abstract

Objective: To identify factors associated with mid-term outcomes (mortality and limb amputation) in patients with infrapopliteal arterial occlusive disease treated by endovascular intervention at the University Medical Center Ho Chi Minh city.

Methods: This was a prospective cohort observational study including 127 patients with infrapopliteal arterial stenosis or occlusion who underwent balloon angioplasty at the University Medical Center Ho Chi Minh city from January 2022 to July 2024.

Results: During mid-term follow-up, underweight patients had a 3.34-fold higher risk of limb amputation compared with those with normal BMI (95% CI: 1.11-11.0; p = 0.031). Patients who died had significantly lower mean eGFR values than survivors (38.5 ± 23.4 ml/min/1,73m² vs. 69.6 ± 27.4 ml/min/1,73m²; p = 0.022). Other factors, including age, sex, and overweight/obesity, were not significant in the multivariate model.

Conclusion: Poor nutritional status and impaired renal function were independent prognostic factors associated with unfavorable mid-term outcomes after endovascular intervention in patients with infrapopliteal arterial occlusive disease. Nutritional screening and renal function preservation should be emphasized in clinical practice to improve outcomes.

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