Articles Vol. 63 No. chuyên đề 1-BV Nhi Thái Bình (2022) 16/09/2022

CLINICAL CHARACTERISTICS AND INITIAL CLINICAL OUTCOMES OF HEPATITIS CAUSED BY CYTOMEGALOVIRUS IN CHILDREN AT NGHE AN OBSTETRICS AND CHILDREN'S HOSPITAL

Tang Xuan Hai1,2, Nguyen Van Tuan1,2, Tran Minh Long1,2
1 Nghe An Obstetrics and Children's Hospital
2 Bệnh viện Sản Nhi Nghệ An
Corresponding author: bstangxuanhai@gmail.com
DOI: 10.52163/yhc.v63iChuyên đề tháng 9.412
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Keywords
Hepatitis, cytomegalovirus (CMV), children.
Abstract

Objectives: Description of clinical characteristics and recommend the initial clinical
outcomes of hepatitis by cytomegalovirus in children at Nghe An Obstetrics and Children’s
Hospital.
Methods: A cross-sectional description of 32 children under 15 years of age diagnosed with
hepatitis due to CMV at Nghe An Obstetrics and Children’s Hospital.
Result: Symptoms of fatigue, anorexia accounted for 96.88%, other symptoms are less
common. 62.50% of patients are anemic due to hepatitis CMV, most of them are mild anemia
(53.13%). 22 patients received antiretroviral therapy with intravenous ganciclovir. The rate
of patients getting better is 68.75%.
Conclusions: Realizing the initial effectiveness of treatment with Ganciclovir by intravenous,
however, a multicenter randomized study is needed to accurately evaluate the effectiveness
and prescribe Ganciclovir treatment.

References
[1]
Andrew AA, Henry BA, “Seroprevalence of Google Scholar
[2]
HHV-8, CMV and EBV among the general Google Scholar
[3]
population in Ghana, West Africa”. BMC Google Scholar
[4]
Infectious Disease, 2008, 8(111), p.1-8. Google Scholar
[5]
Harrison’s Principles of Internal Medicine, Google Scholar
[6]
Medical Publishing House, Volume 1. Google Scholar
[7]
(Translation), 2018, p.1580-1585. Google Scholar
[8]
Nga NQT, Le CMT, “Clinical and subclinical Google Scholar
[9]
characteristics of Cytomegalovirus born Google Scholar
[10]
at the neonatal center of Vietnam National Google Scholar
[11]
Children’s Hospital”, Pediatric journal – Google Scholar
[12]
Volume 14, No 2 (2021). Google Scholar
[13]
Binh TQ, An NTT,“ Acute hepatitis due Google Scholar
[14]
to cytomegalovirus infection in patients Google Scholar
[15]
with persistent fever of unknown etiology”, Google Scholar
[16]
Medical Journal of Ho Chi Minh City Volume Google Scholar
[17]
, No 2 (2012). Google Scholar
[18]
Yukiko S, Naoko K, “Association of Google Scholar
[19]
cytomegalovirus with infantile hepatitis”, Google Scholar
[20]
Microbiology and Immunology. Volume 49, Google Scholar
[21]
No.8. 2005, p.771-777. Google Scholar
[22]
Mihailescu R, Paraschiv S, “Impact of Google Scholar
[23]
highly active antiretroviral therapy on Google Scholar
[24]
cytomegalovirus viraemia, in the absence Google Scholar
[25]
of specific anti-cytomegalovirus therapy”, Google Scholar
[26]
Journal of the International AIDS society, Google Scholar
[27]
(Suppl 10), 2008, p.255.129 Google Scholar
[28]
Marcello L, Tiziana L, “Neonatal Google Scholar
[29]
cytomegalovirus blood load and risk of Google Scholar
[30]
sequelae in symptomatic and asymptomatic Google Scholar
[31]
congenitally infected newborns”, Pediatrics, Google Scholar
[32]
, 117(1), p.76-83. Google Scholar
[33]
Lam NV, Hung VM, Thao NP, “Some Google Scholar
[34]
clinical epidemiological features of acute Google Scholar
[35]
cytomegalovirus hepatitis at the Vietnam Google Scholar
[36]
National Children’s Hospital”, Journal of Google Scholar
[37]
pediatric research and practice - No 5 (10-2018). Google Scholar