Keywords
Hand foot and mouth disease, children.
Abstract
Objectives: To identify potential risk factors for severe hand, foot and mouth disease in children,
were treated in Thai Binh Pediatric Hospital from 6/2020 to 6/2021.
Subjects and methods: This is a retrospective and prospective descriptive study on 1081 HFMD
inpatient treatment in Thai Binh Pediatric Hospital.
Results: The risk factors for severe disease include: Clinicals: high fever more than 39ºC (OR=3),
startle (OR=10.4) with p <0.05. Paraclinicals: White blood cell > 16 000 cell/mm3 (OR=2), with
p<0.05; GOT increased (OR=2.5) and blood sugar increased (OR=3.8), with p < 0.05; EV71: In the
EV71-positive group, the severe group was 34.2%, much higher than the mild group (19.8%). The
difference was statistically significant with p < 0.05.
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