Articles Vol. 63 No. 4 (2022) 08/08/2022

CHARACTERISTICS OF GROUP B STREPTOCOCCUS AND PREVENTIVE TREATMENT WITH ANTIBIOTICS IN 35 -37 WEEK PREGNANT WOMEN AT NGHE AN OBSTETRICS AND PEDIATRICS HOSPITAL 2019

Tang Xuan Hai1,2, Que Anh Tram3,4
1 Nghe An Obstetrics and Pediatrics Hospital
2 Bệnh viện Sản Nhi Nghệ An
3 Nghe An Friendship General Hospital
4 Bệnh viện Hữu nghị Đa khoa Nghệ An
Corresponding author: bstangxuanhai@gmail.com
DOI: 10.52163/yhc.v63i4.363
15 Views
0 Downloads
Abstract

Objectives: The study aims to describe some characteristics of GBS and results of preventive treatment
with antibiotics in 35-37 week pregnant women at Nghe An Obstetrics and Pediatrics Hospital from
2018 to 2019.
Study subjects and methods: The descriptive method combined with analysis and experimental
study in laboratory was employed. Study subjects included pregnant women of 35 - 37 weeks. The
pregnant women had clinical examinations, and were interviewed. Vaginal discharge was taken
for culture and identification of Group B Streptococcus and β hemolytic S-shaped colonies on
blood agar.
Results: The prevalence of Group B streptococcus via clinical examinations was 9.2%. 100% of
the pregnant women used prophylactic antibiotics. 68.5% were injected one shot of antibiotics.
Cephalothin injection was safe for the mothers with 100.0% of the women having no side effects.
Preventive treatment results for the newborn babies after 48 hours of birth were very good,
specifically, no infants had skin inflammation, umbilical cord infection, or pneumonia; only one
infant was infected with E.coli accounting for 1.8%.
Conclusions and recommendations: There is a need to screen and diagnose of group B streptococcus
and do early treatment for pregnant women at the 35th to 37th week to prevent infection for mothers
and newborn babies.

References
[1]
CDC - USA, Sexually transmitted diseases Google Scholar
[2]
treatment guidelines. MMWR, 51 (NO. RR- 6), Google Scholar
[3]
, pp.9- 28. Google Scholar
[4]
CDC - USA, Prevention of perinatal group Google Scholar
[5]
B Streptococcal disease: A public health Google Scholar
[6]
perspective. MMWR, 45(7), 1996, pp. 1-24. Google Scholar
[7]
Ministry of Health, National action plan of health Google Scholar
[8]
care for mothers, children and infants in the Google Scholar
[9]
period 2016 - 2020, 2016, page 15. Google Scholar
[10]
Ministry of Health, Instruction 04 (12003/CTBYT) on strengthening infant care for decreasing Google Scholar
[11]
neonatal mortality rate, 2003. Google Scholar
[12]
Thanh NTV, The prevalence of group B Google Scholar
[13]
streptococcal colonization in pregnant women Google Scholar
[14]
at Tu Du Hospital in June 2006 - June 2007, Google Scholar
[15]
Thesis of Doctor Specialist II, Ho Chi Minh Google Scholar
[16]
City University of Medicine and Pharmacy, 2007. Google Scholar
[17]
Hiep TQ, Study of several characteristics of Google Scholar
[18]
vaginitis caused by group B streptococcal Google Scholar
[19]
colonization among pregnant women examined Google Scholar
[20]
and treated in Bach Mai Hospital. Thesis of Doctor Google Scholar
[21]
Specialist II, Hanoi Medical University, 2011. Google Scholar
[22]
Seale AC, Estimates of the burden of group b Google Scholar
[23]
streptococcal disease Woldwide pregnant women Google Scholar
[24]
Stillbirths, and children. Clinical Infectious Google Scholar
[25]
Disease, 2017, 65. Google Scholar
[26]
Xiaoshan G, Epidemiology of invasive group B Google Scholar
[27]
streptococcal disease in infants from urban area Google Scholar
[28]
of South China, 2011-2014. BMC Infectious Google Scholar
[29]
Diseases, 2018, 18(1), 78 - 90. Google Scholar
[30]
Edwards RK, Clark P, Sistrom CL et al., Google Scholar
[31]
Intrapartum antibiotic prophylaxis 1: relative Google Scholar
[32]
effects of recommended antibiotics on gram Google Scholar
[33]
negative pathogens. Obstet Gynecol, Vol 9, Issue Google Scholar
[34]
, 2002, 534 - 539. Google Scholar
[35]
Schrag SJ, A population - based comparison Google Scholar
[36]
of strategies to prevent early - onset Group B Google Scholar
[37]
streptococcal disease in neonates, New Engl J Google Scholar
[38]
Med 2002, 347 (4), 233 - 9. Google Scholar