Articles Vol. 66 No. 5 20/09/2025

31. HEALTH-RELATED QUALITY OF LIFE IN CHILDREN WITH CHRONIC DISEASES

Cao Thi Thu Huyen1,2,3,4,5,6, Nguyen Hoai Nam3,6, Nguyen Thi Phuong Mai1,4, Nguyen Thi Thanh Mai1,4
1 Department of Pediatrics, Hanoi Medical University
2 Sailt Paul General Hospital
3 Hanoi Children's Hospital
4 Bộ môn Nhi, Trường Đại học Y Hà Nội
5 Bệnh viện Đa khoa Xanh Pôn
6 Bệnh viện Nhi Hà Nội
Corresponding author: thanhmai@hmu.edu.vn
DOI: 10.52163/yhc.v66i5.3116
22 Views
8 Downloads
Keywords
Health-related quality of life, quality of life, children, epilepsy, thalassemia, PedsQLTM 4.0.
Abstract

Objective: To assess the health-related quality of life in children with chronic diseases.

Subjects and methods: A cross-sectional study was conducted on 132 children aged 2-16 years diagnosed with epilepsy or thalassemia at Saint Paul General Hospital. The Vietnamese version of the PedsQL™ 4.0 was used for assessment.

Results: Children with thalassemia had significantly lower physical functioning scores than those with epilepsy (p < 0.001), while children with epilepsy had lower emotional functioning scores than those with thalassemia (p < 0.05). No significant differences were found between the two groups in overall health-related quality of life, social, or school functioning. Overall health-related quality of life was influenced by age, academic performance, disease duration, and treatment duration (p < 0.05), but not by sex or residential area (p > 0.05).

Conclusion: Children with chronic diseases need targeted support to improve health-related quality of life, especially in physical aspects for those with thalassemia and emotional aspects for those with epilepsy. Further research is needed to better understand and enhance health-related quality of life in this population.

References
[1]
Nguyễn Thị Thanh Mai và cộng sự. Khảo sát chất lượng cuộc sống liên quan sức khỏe ở trẻ em khỏe mạnh bằng thang điểm PedsQLTM 4.0 generic core scale, phiên bản Việt Nam. Tạp chí Y học thực hành, 2017, số 6, tr. 181-184. Google Scholar
[2]
Nguyễn Thị Thanh Mai, Phạm Thị Bình. Yếu tố liên quan tới chất lượng cuộc sống liên quan đến sức khỏe của trẻ bị động kinh tại Bệnh viện Nhi trung ương. Tạp chí Nghiên cứu y học, 2022, tr. 222-228. Google Scholar
[3]
Nguyễn Thị Thanh Mai, Trần Thị Ngọc Hòa. Đánh giá chất lượng cuộc sống liên quan đến sức khỏe của bệnh nhân thalassemia tại Bệnh viện Trẻ em Hải Phòng. Tạp chí Nhi khoa, 2017, tr. 50-55. Google Scholar
[4]
Nguyễn Thị Thanh Mai, Đào Thị Nguyệt. Ảnh hưởng của yếu tố bệnh đến chất lượng cuộc sống liên quan sức khỏe ở trẻ Lupus ban đỏ hệ thống. Tạp chí Y học thực hành, 2020. tr. 16-24. Google Scholar
[5]
Adam S, Afifi H, Thomas M et al. Quality of Life Outcomes in a Pediatric Thalassemia Population in Egypt. Hemoglobin, 2017, p. 16-20. Google Scholar
[6]
Deborah M, Michael S. Children with Chronic Health Conditions. MSD Manual Proessional Edition, 2024. Google Scholar
[7]
Momeni M, Ghanbari A, Bidabadi E et al. Health-Related Quality of Life and Related Factors in Children and Adolescents With Epilepsy in Iran. J Neurosci Nurs, 2015, p. 340-345. Google Scholar
[8]
Varni J, Burwinkle T, Self M. Health- related quality of life measurement in pediatric clinical practice: An appraisal and precept for future research and application. Health and quality of life outcomes, 2005, p. 34. Google Scholar