Articles Vol. 66 No. 5 20/09/2025

12. STUDY ON THE RELATIONSHIP BETWEEN CORONARY ARTERY CALCIFICATION LEVEL AND THE RISK OF ACUTE CORONARY SYNDROME RECURRENCE AT THONG NHAT HOSPITAL

Pham Hoang Trong Hieu1,2
1 Interventional Cardiology Center, Tam Anh General Hospital Ho Chi Minh city
2 Trung tâm Tim mạch can thiệp, Bệnh viện Đa Khoa Tâm Anh thành phố Hồ Chí Minh
Corresponding author: kuracistohieu@gmail.com
DOI: 10.52163/yhc.v66i5.3096
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Abstract

Objective: This study aimed to examine the characteristics of coronary artery calcification and evaluate the relationship between the level of calcification and the risk of acute coronary syndrome (ACS) recurrence after intervention at Thong Nhat Hospital.

Subjects and Methods: A cross-sectional descriptive study was conducted from January to June 2025 on 272 patients diagnosed with acute coronary syndrome who had calcified lesions identified by angiography and optical coherence tomography. Data collected included demographic characteristics, cardiovascular risk factors, calcification features, and intervention techniques. Data were analyzed using SPSS 26.0 with a significance level of p < 0.05.

Results: 57% of patients had calcified plaques; among them, 33.2% had diffuse calcification and 20.6% had nodular calcification protruding into the vessel. Special techniques like cutting balloons and rotablation were used in 24.3% and 16.2% of cases, respectively. The rate of optimal stent expansion was 90.4%, and the overall procedural success rate was 94.1%.

Conclusion: The study showed that complex calcified lesions increased intervention difficulty and recurrence risk. Accurate assessment of calcification and selection of appropriate techniques are key to improving treatment outcomes and reducing complications.

References
[1]
Généreux P, Madhavan M.V, Mintz G.S, Maehara A, Palmerini T, LaSalle L, Stone G.W. Ischemic outcomes after coronary intervention of calcified vessels in acute coronary syndromes: pooled analysis from the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) and ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trials. Journal of the American College of Cardiology, 2014, 63 (18), 1845-1854. Google Scholar
[2]
Gharaibeh Y, Lee J, Zimin V.N, Kolluru C, Dallan L.A, Pereira G.T, Wilson D.L. Prediction of stent under-expansion in calcified coronary arteries using machine learning on intravascular optical coherence tomography images. Scientific Reports, 2023, 13 (1), 18110. Google Scholar
[3]
Hoàng Quỳnh Huê, Trần Lan Anh. Đánh giá kết quả can thiệp động mạch vành qua da ở bệnh nhân hội chứng động mạch vành cấp tại Bệnh viện Đa khoa tỉnh Yên Bái năm 2021-2022. Tạp chí Y học Việt Nam, 2023, 529 (1B), 22-26. Google Scholar
[4]
Huỳnh Trung Cang, Lâm Hữu Giang. Khảo sát động mạch vành bị hẹp vôi hóa tại Bệnh viện Đa khoa tỉnh Kiên Giang. Tạp chí Y học Việt Nam, 2024, 541 (1), 387-391. Google Scholar
[5]
Ijichi T, Nakazawa G, Torii S, Nakano M, Yoshikawa A, Morino Y, Ikari Y. Evaluation of coronary arterial calcification-ex-vivo assessment by optical frequency domain imaging. Atherosclerosis, 2015, 243 (1), 242-247. Google Scholar
[6]
Jia H, Abtahian F, Aguirre A.D, Lee S, Chia S, Lowe H, Jang I.K. In vivo diagnosis of plaque erosion and calcified nodule in patients with acute coronary syndrome by intravascular optical coherence tomography. Journal of the American College of Cardiology, 2013, 62 (19), 1748-1758. Google Scholar
[7]
Khalifa A.K.M, Kubo T, Ino Y, Terada K, Emori H, Higashioka D, Akasaka T. Optical coherence tomography comparison of percutaneous coronary intervention among plaque rupture, erosion, and calcified nodule in acute myocardial infarction. Circulation Journal, 2020, 84 (6), 911-916. Google Scholar
[8]
Khalifa A.K.M, Kubo T, Shimamura K, Ino Y, Kishk Y.T, Hasan-Ali H, Akasaka T. Impact of optical coherence tomography imaging on decision-making during percutaneous coronary intervention in patients presented with acute coronary syndromes. Circulation Journal, 2021, 85 (10), 1781-1788. Google Scholar
[9]
Lâm Hữu Giang, Trần Viết An, Huỳnh Trung Cang, Danh Lâm Mỹ Phương, Nguyễn Thế Bảo. Đặc điểm tổn thương và kết quả can thiệp động mạch vành có khoan cắt mảng xơ vữa vôi hóa bằng rotablator ở bệnh nhân hội chứng mạch vành mạn tại Bệnh viện Đa khoa tỉnh Kiên Giang. Tạp chí Y học Việt Nam, 2024, 540 (3), 224-228. Google Scholar
[10]
Lee T, Mintz G.S, Matsumura M, Zhang W, Cao Y, Usui E. Maehara A. Prevalence, predictors, and clinical presentation of a calcified nodule as assessed by optical coherence tomography. JACC: Cardiovascular Imaging, 2017, 10 (8), 883-891. Google Scholar