Articles Vol. 66 No. CĐ8-NCKH 19/08/2025

53. CHARACTERISTICS OF POSTOPERATIVE HYPOCALCEMIA FOLLOWING THYROID SURGERY AT 175 MILITARY HOSPITAL

Le Minh Phong1,2, Nguyen Viet Cuong1,2
1 Military Hospital 175
2 Bệnh viện Quân y 175
Corresponding author: drphonglm175@gmail.com
DOI: 10.52163/yhc.v66iCD8.3009
30 Views
15 Downloads
Keywords
Hypocalcemia thyroid surgery parathyroid gland injury.
Abstract

Objective: To evaluate the characteristics of postoperative hypocalcemia, clinical symptoms, and associated risk factors following thyroid surgery at Military Hospital 175.

Subjects and Methods: A cross-sectional descriptive study combined with a prospective approach was conducted on 44 patients undergoing thyroid surgery at Military Hospital 175 from May 2022 to September 2024.

Results: Among 44 patients, the mean age was 46.3 ± 11.2 years, with females accounting for the majority (79.55%). The majority of patients did not experience hypocalcemia (68.18%), while transient hypocalcemia occurred in 22.73%, and permanent hypocalcemia was observed in 9.09%. Common clinical symptoms included paresthesia (63.64%), tetany (36.36%), cardiac arrhythmia (9.09%), and laryngeal spasm (4.55%). Major risk factors included total thyroidectomy (65.91%), parathyroid gland injury (36.36%), and bleeding or neck edema (15.91%). Significant associations were found between risk factors such as the type of surgery and parathyroid gland injury with postoperative hypocalcemia (p<0.05).

Conclusion: Postoperative hypocalcemia following thyroid surgery was predominantly transient. Total thyroidectomy and parathyroid gland injury were critical risk factors requiring careful management during surgery.

References
[1]
Hoàng Văn Sinh, Phạm Hữu Lư. (2023). Kết quả điều trị phẫu thuật ung thư biểu mô tuyến giáp thể nhú tại bệnh viện hữu nghị Việt Đức. Tạp chí Y học Viet Nam, 532(1), 10–13. Google Scholar
[2]
Del Rio, P., Arcuri, M. F., Cataldo, S., De Simone, B., Pisani, P., & Sianesi, M. (2019). Are we changing our inclusion criteria for minimally invasive video-assisted thyroidectomy? BMC Surgery, 18(1), 25. Google Scholar
[3]
Dolores M. Shoback , John P. Bilezikian , Aline G. Costa. (2016). Presentation of Hypoparathyroidism: Etiologies and Clinical Features. The Journal of Clinical Endocrinology & Metabolism, 101 (6), 1 June 2016, 2300–2312, https://doi.org/10.1210/jc.2015-3909 Google Scholar
[4]
Hoàng Minh Cương, Hoàng Thanh Quang, Nguyễn Anh Tuấn, Hoàng Văn Lâm. (2024). Đánh giá biến chứng sau phẫu thuật tuyến giáp tại Bệnh viện Đa khoa Thái Nguyên. Tạp chí Khoa học Công nghệ Y Dược, 3(1), 14-20. Google Scholar
[5]
Adeel, A.H.A., Khaleel, R.A.A.H., Elwasila, S.A.S.E., & Ismail, M.G.B. (2018). Frequency of hypocalcemia after thyroid surgery in Omdurman Military Hospital. Surgical Science, 14, 111-121. DOI:10.4236/ss.2018.142015. Google Scholar
[6]
Nguyễn Mỹ Duyên, Trần Bảo Ngọc, Nguyễn Thị Hoa, Vy Thị Ngọc Ánh, La Hoàng Thiên. (2021). Nghiên cứu biến chứng hạ calci máu sau phẫu thuật tuyến giáp tại Đại học Y Hà Nội. Báo cáo khoa học nội bộ. Google Scholar
[7]
Alqahtani, S.M., Alsarraj, W.A., & Alrasheed, A.A. (2021). Incidence and Risk Factors of Postoperative Hypocalcemia Following Total Thyroidectomy. Cureus, 13(11), e20006. DOI:10.7759/cureus.20006. Google Scholar
[8]
Suwannasarn, M., & et al. (2018). Incidence of Hypocalcemia Following Thyroid Surgery: A Multicenter Study. Journal of Endocrine Surgery, 19(3), 45-55. Google Scholar
[9]
Testini, M., Rosato, L., Avenia, N., & et al. (2007). The impact of single parathyroid gland autotransplantation during thyroid surgery on postoperative hypoparathyroidism: A multicenter study. Transplant Proc, 39(1), 225-230. Google Scholar