Articles Vol. 66 No. CĐ12-NCKH 01/08/2025

47. BUDGET IMPACT ANALYSIS OF GADOXETATE DISODIUM IN MAGNETIC RESONANCE IMAGING FOR THE DIAGNOSIS OF HEPATOCELLULAR CARCINOMA AND LIVER METASTASES IN VIETNAM

Phung Lam Toi1,2, Do Thi Quynh Trang3,4, Nguyen Thi Mai Phuong3,4, Dao Anh Son3,5, Tran Quoc Khiem3,4, Hoang Minh Tam3,4, Ong The Due3,4, Le Hong Minh6,7
1 University of Medicine and Pharmacy, Vietnam National University, Hanoi
2 Trường Đại học Y Dược, Đại học Quốc gia Hà Nội
3 Health Strategy and Policy Institute, Ministry of Health
4 Viện Chiến lược và Chính sách Y tế, Bộ Y tế
5 iện Chiến lược và Chính sách Y tế, Bộ Y tế
6 The Health Economics Research and Assessment Center
7 Trung tâm Nghiên cứu và Đánh giá Kinh tế Y tế
Corresponding author: toiphunglam@gmail.com
DOI: 10.52163/yhc.v66iCD12.2972
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Abstract

Objective: To examine the budget impact of reimbursing Gd-EOB-DTPA for MRI use in diagnosing hepatocellular carcinoma and liver metastatic cancers in Vietnam.

Methods: A model-based budget impact analysis was conducted from the payer’s perspective over five years, comparing scenarios with and without 100% reimbursement. Input parameters were obtained from the literature and expert consultations.

Results: Full reimbursement would save 2.77 billion VND for hepatocellular carcinoma diagnosis and 17.05 billion VND for liver metastatic cancers diagnosis, mainly owing to reduced treatment costs from earlier and accurate diagnoses. Cost savings were also observed at 30%, 50%, and 70% reimbursement rates.

Conclusion: Reimbursing Gd-EOB-DTPA provides significant economic benefits and improves access to high-precision imaging, supporting its inclusion in the health insurance reimbursement list.