Articles Vol. 66 No. CĐ12-NCKH 01/08/2025

36. CLINICAL, LABORATORY CHARACTERISTICS AND TREATMENT OUTCOMES OF MALARIA IN THE FIRST HALF-TERM AT VIETNAM LEVEL 2 FIELD HOSPITAL No. 6 IN BENTIU, SOUTH SUDAN

Tran Anh Duc1,2,3,4, Pham Hong Khanh1,2,3,4, Hoang The Hung1,2,3,4, Luong Xuan Hoi1,3, Hoang Thi Minh Châu1,3, Nguyen Quang Tung1,3, Nguyen Van Loi3,5, Lam Ngoc Thao1,3, Pham Hong Minh1,3, Vo Nhu Quynh1,3, Tran Quang Canh1,3, Truong Manh Toan1,3, Tran Quang Huy1,3, Tran Yen Linh1,3, Nguyen Viet Nam1,3, Nguyen Tuan Manh1,3
1 Level 2 Field Hospital No. 6, Vietnam Department of Peacekeeping Operations
2 Vietnam Military Medical University
3 Bệnh viện Dã chiến cấp 2 số 6, Cục Gìn giữ hòa bình Việt Nam
4 Học viện Quân y
5 Level 2 Field Hospital No. 6, Vietnam Department of Peacekeeping Operations -
DOI: 10.52163/yhc.v66iCD12.2961
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Keywords
Malaria Plasmodium falciparum Vietnam Level 2 Field Hospital Bentiu South Sudan.
Abstract

Objective: To describe the clinical and laboratory characteristics and treatment outcomes of malaria patients treated at the Vietnam Level 2 Field Hospital No. 6 in Bentiu, South Sudan, during the first six months of the mission.

Subjects and methods: This retrospective descriptive study was conducted on 30 patients diagnosed and treated for malaria at Vietnam Level 2 Field Hospital No. 6 from September 2024 to March 2025. Data were collected from medical records including clinical manifestations, hematology - biochemistry tests, and treatment outcomes.

Results: The mean age of patients was 40.5 ± 7.7 years; 86.7% were male, and 60% were African. Common symptoms included fever (100%), headache (100%), gastrointestinal disturbances (93.3%), and body aches (96.7%). Only 23.3% presented with classic paroxysmal fever. The rapid diagnostic test was positive in 100% of cases, and malaria smear positivity rate was 86.7%. All infections were caused by Plasmodium falciparum. Laboratory abnormalities included thrombocytopenia (mean platelet count: 103.2 ± 57.9 G/L) and mildly elevated liver enzymes. There were no complications or deaths; the recovery rate was 100%, and the average hospital stay was 3.5 ± 1.2 days.

Conclusion: Malaria at Vietnam Level 2 Field Hospital No. 6 presented with diverse and non-specific clinical features. Artemisinin-based therapy remained effective and safe.

References
[1]
World Health Organization. World Malaria Report 2023. Geneva: WHO, 2023. https://www.who.int/publications/i/item/9789240078024 Google Scholar
[2]
United Nations Office for the Coordination of Humanitarian Affairs (OCHA). South Sudan Humanitarian Needs Overview 2023. https://reliefweb.int/report/south-sudan/south-sudan-humanitarian-needs-overview, 2023. Google Scholar
[3]
Bộ Y tế. Quyết định số 2699/QĐ-BYT ngày 26/6/2020 Hướng dẫn chẩn đoán, điều trị và dự phòng sốt rét. Google Scholar
[4]
DHMOSH - Clinical governance unit. Malaria clinical pathway for UN medical clinics, 2022. Google Scholar
[5]
Anjorin S, Okolie E, Yaya S. Malaria profile and socioeconomic predictors among under-five children: an analysis of 11 sub-Saharan African countries. Malaria Journal, 2023 Feb 14, 22 (1): 55. Google Scholar
[6]
Vũ Minh Dương và cộng sự. Đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị người bệnh sốt rét tại Bệnh viện Dã chiến cấp 2 số 4 Việt Nam ở Bentiu, Nam Sudan. Tạp chí Y Dược học quân sự, 2024, số 7: 58-65. Google Scholar
[7]
Min Zhang et al. The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite. Nature communications, 2021 Jul 27, 12 (1): 4563. Google Scholar
[8]
Bria Y.P et al. Significant symptoms and nonsymptom-related factors for malaria diagnosis in endemic regions of Indonesia. International Journal of Infectious Diseases, 2021 Feb, 103: 194-200. Google Scholar
[9]
Sivakorn C, Wilairatana P, Krudsood S, Schultz M.J, Techarang T, Kheawsawaung K, Dondorp A.M. Severe orthostatic hypotension in otherwise uncomplicated Plasmodium vivax infection. Malaria Journal, 2021 Jan, 7, 20 (1): 28. Google Scholar
[10]
He D et al. Epidemiological and Clinical Features of Plasmodium falciparum Malaria in United Nations Personnel in Western Bahr el Ghazal State, South Sudan. PLoS One, 2013, 8 (1): e55220. Google Scholar