THE SITUATION OF ANTIBIOTIC USE AT THONG NHAT HOSPITAL

Objectives: Surveying the situation of antibiotic use at Thong Nhat Hospital. Subjects and methods: retrospective descriptive study on 158 medical records of patients discharged from hospital from February 20^th, 2020 to February 24^th, 2020 (5 days) was kept at the medical records store, Department of general planning, Thong Nhat hospital. Results: In the period of 2019-2020, Penicillin group antibiotics combining beta lactamase inhibitors (90.36% in 2019 and 75.29% in 2020) and C3G + C4G group (86.10% in 2019 and 111,35% in 2020) was most commonly used in the hospital. The antibiotics used on patients consisted of 5 groups, of which, the cephalosporin antibiotic group accounted for the highest proportion of 42.52%; Cefotaxim was used the most with 13.39%. The quinolone group accounted for the lowest percentage (10.50%). Most of the treatment regimen was a combination of 2 antibiotics, accounting for 65.19% and the  change the treatment effectiveness and were worse had a lower proportion, 7.59% and 5.06%, respectively. Hospital transfered patients accounted for a low rate of 1.27%. Conclusion: The group of cephalosporin antibiotics was most commonly used. Most of the treatment regimen was a combination of 2 antibiotics and the majority of patients used oral antibiotics. The average duration of treatment was 11.20 ± 4.32 days. Treatment of recovery and relief/reduction accounted for 51.90% and 34.18% respectively.