Articles Vol. 66 No. 4 25/07/2025

14. ANALYSIS OF DRUG-RELATED PROBLEMS (DRPs) IN THE USE OF ANALGESICS IN CANCER PATIENTS AT THE 108 MILITARY CENTRAL HOSPITAL

Nguyen Thi Hai Yen1,2, Nguyen Tu Son3,4, Nguyen Duc Trung1,2, Nguyen Thi Lien Huong3,4, Luong Thi Thanh Huyen1,2, Le Huy Thai1,2
1 108 Central Military Hospital
2 Bệnh viện Trung ương Quân đội 108
3 Hanoi University of Pharmacy
4 Đại học Dược Hà Nội
Corresponding author: yenyen.hup@gmail.com
DOI: 10.52163/yhc.v66i4.2876
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Keywords
DRPs cancer pain clinical pharmacist PCNE causes of DRPs.
Abstract

Objective: To assess the characteristics of drug-related problems (DRPs) and their causes in pain management for cancer patients at the 108 Military Central Hospital. Methods: A prospective, cross-sectional study was conducted on 471 hospitalized cancer patients. DRPs were identified using the PCNE classification system version 9.1, through medication record review, patient interviews, and multidisciplinary collaboration.

Results: The proportion of patients with DRPs was 22.1%. Among them, the most common DRP was suboptimal treatment effectiveness (74.1%), mainly due to subtherapeutic dosing (45.9%) and patient non-compliance (45.1%). Statistical analysis showed a significant reduction in moderate and severe pain after 24 hours of treatment (p < 0.001).

Conclusion: DRPs in cancer pain management remain common, especially those related to inappropriate dosage selection and patient adherence

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