Articles Vol. 66 No. 4 25/07/2025

7. CLINICAL AND SUBCLINICAL CHARACTERISTICS OF PATIENTS UNDERGOING BREAST RECONSTRUCTION WITH LATISSIMUS DORSI FLAP FOLLOWING MASTECTOMY FOR STAGE I-II BREAST CANCER AT MILITARY HOSPITAL 175

Le Minh Phong1,2, Le Minh Tan1,2
1 Military Hospital 175
2 Bệnh viện Quân y 175
Corresponding author: drphonglm175@gmail.com
DOI: 10.52163/yhc.v66i4.2857
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Abstract

Objective: To evaluate the clinical and paraclinical characteristics of patients undergoing breast reconstruction using latissimus dorsi flap following mastectomy for stage I-II breast cancer at Military Hospital 175.

Subjects and Methods: A descriptive cross-sectional study combined with a prospective approach was conducted on 46 patients diagnosed with stage I-II breast cancer who underwent breast reconstruction using a latissimus dorsi flap following mastectomy at Military Hospital 175, from January 2022 to October 2024.

Results: The study included 46 patients with an average age of 48.3 ± 9.1 years, with the majority falling within the 40-59 age group (54.3%). Most patients were diagnosed at stage I according to the TNM classification (58.7%). Partial mastectomy was the most commonly performed surgery (43.5%), followed by total mastectomy (39.1%), with breast-conserving surgery accounting for the lowest rate (17.4%). Invasive ductal carcinoma was the predominant histopathological type (89.1%). Immunohistochemical analysis was performed in 82.6% of patients, with ER (+) and PR (+) detected in 63.2% and 68.4%, respectively; HER2 (-) accounted for 68.4%, and Ki-67 expression was evenly distributed between ≤14% and >14%, each at 50.0%.

Conclusion: Clinical characteristics such as middle age, stage I-II disease, and the use of breast-conserving or partial mastectomy significantly support the efficacy of breast reconstruction using latissimus dorsi flap, optimizing aesthetic outcomes, functional recovery, and minimizing complications.

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