Articles Vol. 66 No. CĐ11-NCKH 22/08/2025

40. INVESTIGATION ON ANTIBIOTIC USE IN TREATMENT OF SKIN AND SOFT TISSUE INFECTIONS AT BECAMEX INTERNATIONAL HOSPITALINVESTIGATION ON ANTIBIOTIC USE IN TREATMENT OF SKIN AND SOFT TISSUE INFECTIONS AT BECAMEX INTERNATIONAL HOSPITAL

Nguyen Thi Thanh Hien1,2, Nguyen Nhu Ho3,4,5,6
1 Becamex International Hospital
2 Bệnh viện Quốc tế Becamex
3 School of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh city
4 Nguyen Trai Hospital
5 Trường Dược, Đại học Y Dược thành phố Hồ Chí Minh
6 Bệnh viện Nguyễn Trãi
Corresponding author: nhnguyen@ump.edu.vn
DOI: 10.52163/yhc.v66iCD11.2835
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Keywords
Antibiotic antibiotic susceptibility testing skin and soft tissue infections.
Abstract

Objectives: To investigate the pathogens and initial empirical antibiotic use in the treatment of skin and soft tissue infections at Becamex International Hospital.

Materials and methods: A cross-sectional descriptive study was conducted on inpatients with skin and soft tissue infections from May 2022 to December 2022.

Results: The most prevalent pathogen isolated was Staphylococcus aureus (55.6%). The majority of S. aureus strains were Methicillin-resistant (92%). In patients without bacterial culture test, 50.6% received initial empirical antibiotics appropriately according to the guideline. In patients with antibiotic susceptibility testing, only 31% received antibiotics appropriately. Multivariate logistic regression models did not reveal any association between prolonged antibiotic use (> 7 days) and risk factors.

Conclusion: The rate of appropriate initial empirical antibiotic prescription according to both treatment guidelines and susceptibility results remains low. It is necessary to improve initial empirical antibiotic selection, particularly based on microbiological characteristics of local.

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