Articles Vol. 66 No. CĐ11-NCKH 22/08/2025

23. EFFECTIVENESS OF SYNBIOTICS ON HEALTH STATUS OF CHILDREN FROM 24 TO 59 MONTHS OLD IN PHU LUONG DISTRICT, THAI NGUYEN PROVINCE

Nguyen Van Le1,2, Tran Thuy Nga3,4, Huynh Nam Phuong3,4, Nguyen Huu Chinh3,4
1 Ha Dong Medical College
2 Trường Cao đẳng Y tế Hà Đông
3 National Institute of Nutrition
4 Viện Dinh dưỡng Quốc gia
Corresponding author: nguyenvanle78@gmail.com
DOI: 10.52163/yhc.v66iCD11.2817
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Keywords
Disease children 24-59 months old Thai Nguyen province.
Abstract

Objective: To evaluate of the effectiveness of Synbiotics on health status of children aged 24-59 months in Phu Luong district, Thai Nguyen province.

Subjects and methods: A community intervention study was conducted with 606 children meeting research criteria, randomly assigned in intervention and control group. The intervention group used a nutritional product containing Synbiotics for four months with the dose of two sachets per day.

Results: During the four months of intervention, the number of episodes of acute upper respiratory tract infections, acute diarrhea, and functional constipation in the intervention group were 1.7 ± 2.2 episodes, 0.4 ± 1.2 episodes, and 1.4 ± 4.5 episodes, all significantly lower than those in the control group (p < 0.05 - Mann Whitney U test), with corresponding figures of 2.5 ± 3.1 episodes, 0.9 ± 2.2 episodes, and 2 ± 5.5 episodes.

Conclusion: The intervention study using a nutritional product containing Synbiotics showed significant effects after four months of intervention. Children who consumed the product experienced a reduction in the number of episodes and the risk of acute upper respiratory tract infections, acute diarrhea, and functional constipation. Therefore, the product and the intervention method proposed in this study are appropriate to improve disease conditions in children aged 24 to 59 months.

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