Articles Vol. 66 No. VoL 66. English Version No 1, 2025 15/08/2025

12. CLINICAL AND PATHOLOGICAL CHARACTERISTICS OF DIFFERENTIATED THYROID CARCINOMA AT MILITARY HOSPITAL 175

Le Minh Phong1, Ha Bao2, Nguyen Thanh Chung3
1 Military Hospital 175
2 Can Tho Oncology Hospital
3 Le Huu Trac National Burn Hospital
Corresponding author: drphonglm175@gmail.com
DOI: 10.52163/yhc.v66ienglish.2745
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Keywords
Thyroid cancer differentiated type capsular invasion.
Abstract

Objective: To describe the clinical and histopathological characteristics of differentiated thyroid cancer at Military Hospital 175.

Subjects and Methods: A descriptive cross-sectional study combined with a prospective design was conducted on 42 patients diagnosed with differentiated thyroid cancer at Military Hospital 175 from July 2022 to January 2024.

Results: The mean age of patients was 45.8 ± 9.6 years, with a predominance of females (71.4%). Papillary carcinoma accounted for the majority of histopathological types (90.5%), with capsular invasion in 11.9% and invasion of adjacent organs in 4.8% of cases. The disease stages were predominantly T1 and T2 (64.3%), with no lymph node metastasis (76.2%) and no distant metastasis (97.6%). There were significant associations between age, gender, tumor size, and the status of lymph node metastasis and capsular invasion (p<0.05). Within one year post-surgery, the recurrence-free rate was 92.9%, with local recurrence at 4.7% and distant recurrence at 2.4%.

Conclusion: Differentiated thyroid cancer has a favorable prognosis with a high one-year recurrence-free rate. However, risk factors such as tumor size and invasion status should be carefully considered in diagnosis and treatment.

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