Articles Vol. 66 No. VoL 66. English Version No 1, 2025 15/08/2025

8. LIVER CANCER IN VIETNAM AND ASIA FROM 2013 TO 2023: EPIDEMIOLOGICAL TRENDS AND CONTRIBUTING RISK FACTORS – A SCOPING REVIEW

Hoang Phuong Thao1,2, Nguyen Le Tuan Anh2, Le Thi Huong2
1 Vietnam National Cancer Hospital
2 Hanoi Medical University
Corresponding author: thaohp1@bvk.org.vn
DOI: 10.52163/yhc.v66ienglish.2740
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Keywords
liver cancer Vietnam, Asia incidence mortality risk factors HBV aflatoxins
Abstract

Objectives: This scoping review explored liver cancer incidence, mortality trends, and risk factors in Vietnam and Asia from 2013 to 2023, using the PCC framework (Population, Concept, Context).

Methods: Following PRISMA-ScR guidelines, a literature search was conducted using PubMed, Web of Science, and Vietnamese sources. Eligible studies were selected and synthesized thematically to provide a comprehensive view.

Results: Thirty-three studies were included. Vietnam and several Asian countries reported some of the highest liver cancer rates globally, with age-standardized incidence rates reaching 20.2 per 100,000 in Vietnam, 25.7 in China, and 31.0 in Mongolia, according to GLOBOCAN 2022 data. Major risk factors include HBV/HCV infections, aflatoxin exposure, alcohol, metabolic disorders, environmental pollution, and poor healthcare access.

Conclusions: The burden of liver cancer remains high in Vietnam and Asia. Comprehensive public health interventions addressing both infectious and lifestyle-related factors, along with improvements in healthcare infrastructure, are urgently needed to address the growing health challenges.

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