Objectives: Identify some factors related to diarrhea after using antibiotics. Methods: A cross-sectional descriptive study with 236 children under 6 years of age with diarrhea after taking antibiotics treatment at the National Children's Hospital from October 2017 to September 2018. Results: Common age is 7-24 months. The main antibiotic used is Cephalosporin. The time to end diarrhea symptoms was different between the group with and without inpatient treatment at the primary level (p<0.05). The mean duration to end diarrhea symptoms significant associated with groups with other infections (p<0.05). Conclusion: The duration of diarrhea symptoms associated with the history of treatment at the primary level and associated infection groups.
FACTORS RELATED TO ANTIBIOTIC-ASSOCIATED DIARRHEA AMONG CHILDREN UNDER 6 YEARS OLD AT THE NATIONAL CHILDREN’S HOSPITAL
31
Views
0
Downloads
Keywords
Diarrhea, antibiotics, children under 6.
Abstract
References
[1]
D’Ostroph AR, So TY, Treatment of pediatric Clostridium difficile infection: a review on treatment efficacy and economic value, Infection and Drug Resistance, 2017; 10:365–75.
Google Scholar
[2]
Turck D, Bernet J, Marx J et al., Incidence and risk factors of oral antibiotic-associated diarrhea in an outpatient pediatric population, Journal of Pediatric Gastroenterology and Nutrition, 2003; 37(1), 22-26.
Google Scholar
[3]
Tyler Y, Ran D, Goldman, Probiotics for antibiotic-associated diarrhea in children, Canadian Family Physician, 2020; 66(1): 37–39.
Google Scholar
[4]
Wistrom J, Frequency of antibiotic-associated diarrhoea in 2462 antibiotic-treated hospitalized patients: a prospective study, Journal of Antimicrobial Chemotherapy, 2001; 47(1): 43-50.
Google Scholar
[5]
Guo Q, Goldenberg JZ, Humphrey C et al., Probiotics for the prevention of pediatric antibiotic-associated diarrhea, Cochrane Database of Systematic Reviews, 2019; 30;4(4):CD004827.
Google Scholar
[6]
Mantegazza C, Molinari P, D’Auria E et al., Probiotics and antibiotic-associated diarrhea in children: a review and new evidence on Lactobacillus rhamnosus GG during and after antibiotic treatment, Pharmacological Research, 2018; 128:63–72.
Google Scholar
[7]
Musher DM, Lorgan N, Mehendiratta V et al., Clostridium difficile colitis that fails conventional metronidazole therapy: response to nitazoxanide, Journal of Antimicrobial Chemotherapy, 2007; 59, 705-710.
Google Scholar
[8]
McFarland LV, Beneda HW, Clarridge JE et al., Implications of the changing face of C. difficile disease for health care practitioners. Am. J. Infect. Control, 2007; 35(4), 237-253.
Google Scholar
[9]
Damrongmanee A, Ukarapol N, Incidence of antibiotic-associated diarrhea in a pediatric ambulatory care setting. Journal of the Medical Association of Thailand, 2007; 90(3), 513-517.
Google Scholar
[10]
Naflesia BOC , Luciano APF, Francisco JP et al., A randomized formula controlled trial of Bifidobacterium lactis and Streptococcus thermophilus for prevention of antibiotic-associated diarrhea in infants, Journal of Clinical Gastroenterology, 2005; 39(5):385-9.
Google Scholar