Articles Vol. 63 No. 1 (2022) 06/01/2022

EFFICACY AND SAFETY OF MICROPULSE TRANSSCLERAL DIODE LASER CYCLOPHOTOCOAGULATION IN ABSOLUTE GLAUCOMA

Hoang Thi Kieu Hau1,2, Pham Thi Thuy Tien3,4, Nghiệp Nghiep3,4, Nguyen Pham Trung Hieu5,6
1 General Hospital of Binh Duong Province
2 BV ĐK tỉnh Bình Dương
3 Eye Hospital HCMC
4 BV Mắt TP HCM
5 Medical and Pharmaceutical University of HCMC
6 Trường ĐH Y Dược TP HCM
Corresponding author: bskieuhaubd@gmail.com
DOI: 10.52163/yhc.v63i1.261
20 Views
0 Downloads
Abstract

Purposess: To evaluate the effectiveness of lowering intraocular pressure and the safety of Micropulse Transscleral diode laser cyclophotocoagulation (MP-TSCPC) with a duty cycle of 31,3% in absolute glaucoma patients.

Methods: A prospective interventional study was performed on 64 eyes from October 2020 to April 2021 at the Ho Chi Minh City Eye Hospital.

Results: Sixty four patients including 26 females and 38 males were recruited with the mean age 56.1±2.1. The mean IOP at pre- and post-opereration was 45.9±11.0 and 25.8±13.8mmHg, respectively. The average IOP reduced 42.4%, 33.5%, 39.1% and 45.5% from baseline after surgery at 1 week, 1 month, 3 months and 6 months (p value <0,001). 93,7% of patients improved pain symptoms after MP-TSCPC. The mean number of antiglaucoma medication was down from 3.5 ± 0.69 at the begining to 1.6 ± 0.78 at the end of the study. No serious complications were recorded.

Conclusion: Micropulse Transscleral diode laser cyclophotocoagulation with a duty cycle of 31,3% is an effective and safe method to lower intraocular pressure and relieve pain in absolute glaucoma.

References
[1]
Aquino MC, Barton K, Tan AM et al., "Micropulse versus continuous wave transscleral diode cyclophotocoagulation in refractory glaucoma: a randomized exploratory study". Clin Exp Ophthalmol, 2015, 43 (1), 40-6. Google Scholar
[2]
Benhatchi N, Bensmail D, Lachkar Y, "Benefits of SubCyclo Laser Therapy Guided by High-frequency Ultrasound Biomicroscopy in Patients With Refractory Glaucoma". J Glaucoma, 2019, 28 (6), 535-539. Google Scholar
[3]
Chen MF, Kim CH, Coleman AL, "Cyclodestructive procedures for refractory glaucoma". Cochrane Database Syst Rev, 2019, 3 (3), Cd012223. Google Scholar
[4]
Emanuel ME, Grover DS, Fellman RL et al., "Micropulse Cyclophotocoagulation: Initial Results in Refractory Glaucoma". J Glaucoma, 2017, 26 (8), 726-729. Google Scholar
[5]
Kuchar S, Moster MR, Reamer CB et al., "Treatment outcomes of micropulse transscleral cyclophotocoagulation in advanced glaucoma". Lasers Med Sci, 2016, 31 (2), 393-6. Google Scholar
[6]
Li Z, Song Y, Chen X et al., "Biological Modulation of Mouse RPE Cells in Response to Subthreshold Diode Micropulse Laser Treatment". Cell Biochem Biophys, 2015, 73 (2), 545-552. Google Scholar
[7]
Pastor SA, Singh K, Lee DA et al., "Cyclophotocoagulation: a report by the American Academy of Ophthalmology". Ophthalmology, 2001, 108 (11), 2130-8. Google Scholar
[8]
Sanchez FG, Lerner F, Sampaolesi J et al., "Efficacy and Safety of Micropulse® Transscleral Cyclophotocoagulation in Glaucoma". Arch Soc Esp Oftalmol, Eficacia y seguridad de la ciclofotocoagulación transescleral con micropulsos en el tratamiento del glaucoma., 2018, 93 (12), 573-579. Google Scholar
[9]
Tham YC, Li X, Wong TY et al., "Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis". Ophthalmology, 2014, 121 (11), 2081-90. Google Scholar
[10]
Zaarour K, Abdelmassih Y, Arej N et al., "Outcomes of Micropulse Transscleral Cyclophotocoagulation in Uncontrolled Glaucoma Patients". J Glaucoma, 2019, 28 (3), 270-275. Google Scholar