Articles Vol. 66 No. CĐ8-NCKH 22/08/2025

20. SOME FACTORS RELATED TO THE EFFICACY OF THE HERBAL FORMULA HOANG KY BO HUYET THANG COMBINED WITH ACUPRESSURE AND MASSAGE IN PATIENTS WITH CHRONIC CEREBRAL CIRCULATORY INSUFFICIENCY TREATED AT THAI BINH PROVINCIAL HOSPITAL OF TRADITIONAL MEDICINE IN 20

Bui Quoc Hung1,2, Phi Thi Ngoc1,2, Mai Duc Han1,2
1 Thai Binh University of Medicine and Pharmacy
2 Trường Đại học Y Dược Thái Bình
Corresponding author: hungbui031293@gmail.com
DOI: 10.52163/yhc.v66iCD8.2564
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Keywords
Chronic cerebral circulatory insufficiency Hoang ky bo huyet thang acupressure massage treatment efficacy traditional medicine.
Abstract

Objective: To determine some factors related to the treatment effectiveness of the combined regimen of Hoang ky bo huyet thang and acupressure massage on patients with chronic cerebral circulatory insufficiency at Thai Binh provincial Hospital of Traditional Medicine.

Method: A cross-sectional descriptive study was conducted on 30 chronic cerebral circulatory insufficiency patients treated at Thai Binh provincial Hospital of Traditional Medicine from May 2023 to December 2023 with Hoang ky bo huyet thang (1 decoction/day) combined with acupressure massage for 15 days.

Results: The treatment effectiveness rated as good reached 80%. Factors significantly associated with good effectiveness included: female gender (OR = 25.0), absence of other chronic diseases (OR = 10.0), and duration of chronic cerebral circulatory insufficiency under 6 months (OR = 7.6) (p < 0.05).

Conclusion: The combined regimen of Hoang ky bo huyet thang and acupressure massage demonstrated good treatment efficacy in the majority of chronic cerebral circulatory insufficiency patients. Female gender, absence of chronic comorbidities, and shorter disease duration are favorable prognostic factors for treatment effectiveness.

References
[1]
Calabrese V, Giordano J, Signorile A et al. Major pathogenic mechanisms in vascular dementia: Roles of cellular stress response and hormesis in neuroprotection. J Neurosci Res, 2016, 94 (12): 1588-1603. Google Scholar
[2]
Sheu J.R, Geraldine P, Yen M.H. Bioactives and traditional herbal medicine for the treatment of cardiovascular/cerebrovascular diseases. Evid Based Complement Alternat Med, 2014: 495323. Google Scholar
[3]
Xu Z, Feng X, Li L et al. Efficacy and safety of oral traditional Chinese patent medicine for chronic cerebral circulation insufficiency patients: A protocol for a systematic review and network meta-analysis. Medicine (Baltimore), 2019, 98 (27): e16175. Google Scholar
[4]
Lý Đông Viên. Nội ngoại thương biện hoặc luận. Nhà xuất bản Phương Đông, 2014. Google Scholar
[5]
Chen Y.W, Wang H.H. The effectiveness of acupressure on relieving pain: a systematic review. Pain Manag Nurs, 2014, 15 (2): 539-50. Google Scholar
[6]
Dinh Duy Dung, Dinh Nhan Nguyen, Thi Xuan Huong Hoang et al. Outcomes of massage and acupressure therapy in taking care of patients with shoulder-neck strain syndrome at the Military Institute of Traditional Medicine in 2022. Tạp chí Khoa học Điều dưỡng, 2023, 6 (01): 115-124. Google Scholar
[7]
Hội đồng Dược điển Việt Nam. Dược điển Việt Nam. Nhà xuất bản Y học, Hà Nội, 2022. Google Scholar
[8]
Hadjiev D. Impedance Methods for Investigation of Cerebral Circulation, in Progress in Brain Research, John Stirling Meyer & J.P Schadé, Editors. Elsevier, 1972, 25-85. Google Scholar
[9]
Chen X, Yang T, Luo Y et al. Methodological and reporting quality evaluation of Buyang Huanwu decoction for experimental cerebral ischemia-reperfusion injury: a systematic review. Naunyn Schmiedebergs Arch Pharmacol, 2023, 396 (5): 831-849. Google Scholar
[10]
Zhang Z.Q, Song J.Y, Jia Y.Q et al. Buyanghuanwu decoction promotes angiogenesis after cerebral ischemia/reperfusion injury: mechanisms of brain tissue repair. Neural Regen Res, 2016, 11 (3): 435-40. Google Scholar
[11]
Wang L, Su X.T, Cao Y et al. Potential mechanisms of acupuncture in enhancing cerebral perfusion of ischemic stroke. Front Neurol, 2022, 13: 1030747. Google Scholar
[12]
Zhou D, Meng R, Li S.J et al. Advances in chronic cerebral circulation insufficiency. CNS Neurosci Ther, 2018, 24 (1): 5-17. Google Scholar
[13]
Shields Corbin A, Xi Wang, Denise C Cornelius. Sex differences in cardiovascular response to sepsis, 2023, 324 (2): C458-C466. Google Scholar
[14]
She Rui, Zhongrui Yan, Yanlei Hao et al. Comorbidity in patients with first-ever ischemic stroke: Disease patterns and their associations with cognitive and physical functionVolume, 2022, 14. Google Scholar
[15]
Simić-Panić D, Bošković K, Milićević M et al. The Impact of Comorbidity on Rehabilitation Outcome after Ischemic Stroke. Acta Clin Croat, 2018, 57 (1): 5-15. Google Scholar
[16]
Kimura S, Iwata M, Takase H et al. Oxidative stress and chronic cerebral hypoperfusion: An overview from preclinical rodent models. J Cereb Blood Flow Metab, 2025, 45 (3): 381-395. Google Scholar
[17]
Rajeev V, Fann D.Y, Dinh Q.N et al. Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment. Theranostics, 2022, 12 (4): 1639-1658. Google Scholar