Articles Vol. 66 No. CĐ5-NCKH 06/05/2025

1. THE CLINICAL CHARACTERISTICS OF PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE AT UNIVERSITY MEDICAL CENTER HO CHI MINH CITY FACILITY 3

Truong Hoang Nha Khuyen1,2, Le Thi Hong Ngoc1,2, Bui Thi Yen Nhi3,4, Tran Hoa An1,2, To Ly Cuong1,2, Tran Quang Tu1,2
1 University of Medicine and Pharmacy at Ho Chi Minh city
2 Đại học Y Dược thành phố Hồ Chí Minh
3 University Medical Center Ho Chi Minh city facility 3
4 Bệnh viện Đại học Y Dược thành phố Hồ Chí Minh cơ sở 3
Corresponding author: tranquangtu@ump.edu.vn
DOI: 10.52163/yhc.v66iCD5.2434
37 Views
18 Downloads
Abstract

Objective: To investigate the clinical characteristics of patients seeking examination and treatment for GERD at University Medical Center Ho Chi Minh City facility 3.

Materials and methods: A cross-sectional descriptive study using retrospective data was conducted on 192 prescriptions/non-medication orders from patients with GERD seeking examination and treatment at University Medical Center Ho Chi Minh City facility 3 from January 2024 to December 2024.

Results: Female patients accounted for the majority (60.9%), and the median age of female patients with GERD was 40.0 (31.5-57.0), which was significantly higher than in males at 35.0 (29.0-48.0), p = 0.009. Most women with GERD had a normal BMI (73.5%), while men with GERD had higher rates of overweight (38.7%) and obesity (29.3%), p = 0.001. The median blood pressure of male GERD patients was 125.0 (118.0-136.0) mmHg, higher than the median blood pressure of female GERD patients at 120.0 (108.0-128.0) mmHg, p = 0.001. Most GERD patients exhibited symptoms from both traditional medicine (77.1%) and modern medicine (93.2%). Bitter taste in the mouth was more common in older adults (13.8%), while bloating, nausea, and vomiting were more common in younger patients. Gastroduodenitis was a common comorbid condition in GERD patients (24%).

Conclusion: There is a gender-based difference in age, BMI, blood pressure, and comorbidities in GERD patients, as well as a difference in GERD symptoms across age groups.

References
[1]
Fass R, Gastroesophageal Reflux Disease, N Engl J Med, 2022, 387 (13): 1207-1216. Google Scholar
[2]
Eusebi L.H, Ratnakumaran R, Yuan Y et al, Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis, Gut, 2018, 67 (3): 430-440. Google Scholar
[3]
Nguyễn Thị Bay, Lê Thị Lan Hương, Bệnh học và điều trị nội khoa kết hợp đông tây y, tập 2, Nhà xuất bản Y học, thành phố Hồ Chí Minh, 2022, trang 19-41. Google Scholar
[4]
Nguyễn Thị Ngọc Linh, Nguyễn Thanh Tú, Khảo sát thể bệnh y học cổ truyền của bệnh nhân trào ngược dạ dày thực quản tại Khoa Khám bệnh, Bệnh viện Đa khoa Y học cổ truyền Hà Nội, Tạp chí Y học Việt Nam, 2022, 520 (1A): 209-212. Google Scholar
[5]
Nguyễn Chí Tùng, Nguyễn Viết Lợi, Hồ Ngọc Điệp và cộng sự, Khảo sát một số đặc điểm lâm sàng bệnh trào ngược dạ dày thực quản có tổn thương thực quản, Tạp chí Y Dược thực hành 175, 2023, 32 (8): 61-68. Google Scholar
[6]
Bordin D.S, Livzan M.A, Gaus O.V et al, Drug-Associated Gastropathy: Diagnostic Criteria, Diagnostics (Basel), 2023, 13 (13): 2220. Google Scholar
[7]
Wang K, Wang S, Chen X, The Causal Effects between Mood Swings and Gastrointestinal Diseases: A Mendelian Randomization Study, Alpha Psychiatry, 2024, 24 (4): 533-540. Google Scholar
[8]
Wang J.J, Liang K.L, Lin W.J et al, Influence of age and sex on taste function of healthy subjects, PLoS One, 2020, 15 (6): e0227014. Google Scholar
[9]
Shaheen N.J, Falk G.W, Iyer P.G et al, Diagnosis and Management of Barrett's Esophagus: An Updated ACG Guideline, Am J Gastroenterol, 2022, 117 (4): 559-587. Google Scholar
[10]
Yuan S, Chen J, Ruan X et al, Smoking, alcohol consumption, and 24 gastrointestinal diseases: Mendelian randomization analysis, Elife, 2023, 12: e84051. Google Scholar