Articles Vol. 66 No. CĐ7-HNKH Bệnh viện K 22/05/2025

20. SURVEY ON QUALITY OF LIFE IN OVARIAN CANCER PATIENTS UNDERGOING POSTOPERATIVE CHEMOTHERAPY AT INTERNAL MEDICINE DEPARTMENT 6, K HOSPITAL IN 2024

Nguyen Thi Linh1,2, Nguyen Thi Hong1,2, Dang Tien Giang3,4
1 K Hospital
2 Bệnh viện K
3 Department of Internal Medicine 6, K Hospital
4 Khoa Nội 6, Bệnh viện K
Corresponding author: bsdtgiang@gmail.com
DOI: 10.52163/yhc.v66iCD7.2401
16 Views
14 Downloads
Keywords
EORTC QLQ-C30 ovarian cancer
Abstract

Objective: This study aimed to investigate factors associated with the quality of life (QoL) of ovarian cancer patients after chemotherapy at the Internal Medicine Department 6, K Hospital in 2024.

Subjects and Methods: A prospective descriptive study was conducted on 120 ovarian cancer patients undergoing chemotherapy at Internal Medicine Department 6, K Hospital from March 2024 to December 2024. QoL was assessed using the EORTC QLQ-C30 questionnaire at three time points: before treatment, after three chemotherapy cycles, and upon completion of treatment.

Results: A total of 120 patients participated, with a mean age of 52.7 ± 8.5 years. The overall QoL score before treatment was 55.4 ± 12.3, improving to 63.1 ± 9.8 after three chemotherapy cycles, but slightly decreasing to 60.5 ± 10.2 at the end of treatment. Fatigue, nausea, pain, and insomnia were the most common symptoms affecting QoL. The physical function score started at 52.4 ± 11.2, increased to 61.7 ± 10.9 after three cycles, and slightly declined to 59.2 ± 11.0 at the end of treatment. Similar trends were observed in emotional and social function scores. Marital status and educational level showed a significant correlation with QoL scores (p < 0.05).

Conclusion: The study provides important insights into improving comprehensive care and support to enhance the quality of life for ovarian cancer patients after chemotherapy.

References
[1]
Wilson IB, Cleary PD. Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. JAMA. 1995;273(1):59-65. Google Scholar
[2]
Guyatt GH, Feeny DH, Patrick DL. Measuring health-related quality of life. Ann Intern Med. 1993;118(8):622-629. doi:10.7326/0003-4819-118-8-199304150-00009 Google Scholar
[3]
Testa MA, Simonson DC. Assessment of quality-of-life outcomes. N Engl J Med. 1996;334(13):835-840. doi:10.1056/NEJM199603283341306 Google Scholar
[4]
Oldridge N, Gottlieb M, Guyatt G, Jones N, Streiner D, Feeny D. Predictors of health-related quality of life with cardiac rehabilitation after acute myocardial infarction. J Cardiopulm Rehabil. 1998;18(2):95-103. doi:10.1097/00008483-199803000-00002 Google Scholar
[5]
Boscolo-Rizzo P, Maronato F, Marchiori C, Gava A, Da Mosto MC. Long-term quality of life after total laryngectomy and postoperative radiotherapy versus concurrent chemoradiotherapy for laryngeal preservation. Laryngoscope. 2008;118(2):300-306. doi:10.1097/MLG.0b013e31815a9ed3 Google Scholar
[6]
Thatcher N, Hopwood P, Anderson H. Improving quality of life in patients with non-small cell lung cancer: research experience with gemcitabine. Eur J Cancer. 1997;33 Suppl 1:S8-13. doi:10.1016/s0959-8049(96)00336-x Google Scholar
[7]
Pötter R, Tanderup K, Schmid MP, et al. MRI-guided adaptive brachytherapy in locally advanced cervical cancer (EMBRACE-I): a multicentre prospective cohort study. The Lancet Oncology. 2021;22(4):538-547. doi:10.1016/S1470-2045(20)30753-1 Google Scholar
[8]
Montazeri A, McEwen J, Gillis CR. Quality of life in patients with ovarian cancer: current state of research. Support Care Cancer. 1996;4(3):169-179. doi:10.1007/BF01682336 Google Scholar
[9]
Kornblith AB, Thaler HT, Wong G, et al. Quality of life of women with ovarian cancer. Gynecol Oncol. 1995;59(2):231-242. doi:10.1006/gyno.1995.0014 Google Scholar
[10]
Tú NQ, Thu VT, Phúc PĐ, Ba ĐC, Minh ĐTN. Đánh giá chất lượng cuộc sống ở người bệnh ung thư tại Khoa Ung thư tổng hợp, Bệnh viện Trung ương Quân đội 108. Journal of 108 - Clinical Medicine and Phamarcy. Published online August 12, 2022. doi:10.52389/ydls.v17iDB8.1332 Google Scholar