Articles Vol. 66 No. CĐ4-NCKH 15/04/2025

17. VACUUM BLOOD TUBES: DEVELOPMENT AND APPLICATIONS IN MODERN MEDICINE

Nguyen Minh Son1,2, Lam Kien Thanh1,2, Phan Viet Anh Viet Vuong3,4, Le Van Chuong1,2
1 Faculty of Medical Technology, Van Lang University
2 Khoa Kỹ thuật Y học, Trường Đại học Văn Lang
3 Research and Development Department, Wembley Medical Company
4 Phòng Nghiên cứu và Phát triển, Công ty Cổ phần Nhà máy Wembley Medical
Corresponding author: chuongmedtech@ump.edu
DOI: 10.52163/yhc.v66iCD4.2335
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Keywords
Blood specimen collection preanalytical phase hemolysis sample quality clinical laboratory techniques
Abstract

Objective: To review the development, characteristics, advantages, and challenges of vacuum blood collection tubes in clinical testing compared to traditional methods.

Methods: Literature search was conducted on PubMed, from 2010-2024 using keywords: “vacuum blood collection tubes”, “preanalytical errors”, “hemolysis”, “sample quality”… Selection criteria included studies on sample quality, preanalytical factors, and hemolysis reduction solutions.

Results: Vacuum blood collection tubes significantly improve sample quality, efficiency, and safety compared to traditional methods. Hemolysis remains a major challenge, especially in emergency departments (rates up to 35%), and pediatric specimens. Using smaller volume tubes (2 mL versus 6 mL) can decrease hemolysis rates from 11.8% to 2.9%. Proper tube selection, correct sampling technique, and staff training are important factors affecting sample quality.

Conclusion: Vacuum blood collection tubes provide significant benefits in reducing pre-analytical errors, enhancing safety protocols, and cost-effectiveness. Current research trends focus on developing patient-specific tubes and integration with automated systems.

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