Articles Vol. 66 No. CĐ2-NCKH 24/03/2025

6. EVALUATION OF NUTRITIONAL STATUS IMPROVEMENT AFTER MANDIBULAR DISTRACTION OSTEOGENESIS IN SEVERE PIERRE ROBIN SEQUENCE

Dang Hoang Thom1,2,3,4, Duong Huy Luong2,4,5,6, Mai Thi Huong1,3, Dang Thi Ha1,3, Lu Thi Ha1,3, Bui Thi Hoa1,3, Quach Thi Hien1,3
1 National Children's Hospital
2 Hanoi Medical University
3 Bệnh viện Nhi trung ương
4 Trường Đại học Y Hà Nội
5 Ministry of Health
6 Bộ Y tế
Corresponding author: Thommdplastic@gmail.com
DOI: 10.52163/yhc.v66iCĐ2.2189
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Keywords
Pierre Robin Sequence nutrition mandibular distraction osteogenesis
Abstract

Objective: This study evaluated improvements in preoperative and postoperative nutritional status in infants with severe Pierre Robin Sequence (PRS) undergoing mandibular distraction osteogenesis (MDO).

Methods: A prospective, uncontrolled clinical interventional study was conducted on 102 severe PRS patients who underwent bilateral MDO at the Craniofacial and Plastic Surgery Department, Vietnam National Children's Hospital, from 2019 to 2023.

Results: Among the patients, 35.3% had inflammation, and 55.9% were malnourished. All required preoperative nutritional support. By the end of the activation phase, 82.4% could feed orally, and by three months postoperatively, all achieved normal feeding ability. Average birth weight was 2,917.65 ± 592.62 grams, increasing to 3,496.14 ± 1,008.43 grams at surgery. After device removal, weight rose to 4,650.23 ± 1,017.5 grams (159.4% increase from birth weight), reaching 8,450.3 ± 1,147.1 grams at nine months (289.68% increase). These results indicate significant improvements in nutritional status and weight gain comparable to healthy infants.

Conclusion: MDO is a safe, effective, and feasible procedure that significantly enhances the physical condition and nutritional status of infants with severe PRS.

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