Articles Vol. 66 No. CĐ3-HNKH Ký Sinh Trùng VN lần thứ 51 24/03/2025

36. ASSESSMENT OF COMPLIANCE WITH ANTIVIRAL TREATMENT AND SOME RELATED FACTORS OF PATIENTS WITH CHRONIC HEPATITIS B AT NGHE AN GENERAL FRIENDSHIP HOSPITAL

Que Anh Tram1,2, Nguyen Thi Dieu Linh1,2, Tran Anh Dao1,2
1 Nghe An Friendship General Hospital
2 Bệnh viện Hữu Nghị Đa khoa Nghệ An
Corresponding author: tramlien@gmail.com
DOI: 10.52163/yhc.v66iCĐ3.2158
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Keywords
Hepatitis B Antiviral treatment Treatment adherence
Abstract

Objective: To determine the status of adherence to antiviral treatment and some factors related to adherence to antiviral treatment of patients with chronic hepatitis B at Nghe An General Hospital in 2023.

Subjects and methods of research: Cross-sectional description. The study subjects were patients diagnosed with chronic hepatitis B who were being managed and treated with antiviral drugs at the Tropical Diseases Clinic, Nghe An General Hospital.  

Results: The results of the study showed that the adherence to antiviral treatment of chronic hepatitis B patients at the Tropical Diseases Clinic, Nghe An General Hospital was 39.5%. Adherence to treatment was associated with marital status (p < 0.01) and distance from home to hospital (p = 0.05). Patients who had daily phone reminders to take hepatitis B antiviral drugs had higher adherence to treatment than patients who did not have daily phone reminders to take medication (p = 0.01).

Conclusion: The rate of adherence to antiviral treatment assessed by the CEAT-HBV questionnaire was still low at 39.5%. Treatment adherence was associated with marital status, distance from home to hospital, and daily phone reminders for taking medication.

References
[1]
. CDC US (2006), Implementation of newborn hepatitis B vaccinationWorldwide, Morb Mortal Weekly Rep. Google Scholar
[2]
. WHO (2015), Framework for Global Action: Prevention & Control of Viral Hepatitis Infection Google Scholar
[3]
. Ngô Quý Châu, Nguyễn Đạt Anh, Phạm Quang Vinh (2020), Bệnh học Nội khoa, Nhà xuất bản Y học. Google Scholar
[4]
. United States Cancer Statistics - Mortality Incidence Rate Ratios: 1999 - 2016, WONDER Online Database. United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute; 2019. Google Scholar
[5]
. Abreu RM, da Silva Ferreira C, Ferreira AS, et al (2016). Assessment of Adherence to Prescribed Therapy in Patients with Chronic Hepatitis B. Infect Dis Ther, 5(1): 53-64. Google Scholar
[6]
. Bùi Phan Quỳnh Phương, Lê Minh Châu, Cao Minh Nga (2017), Phát hiện đột biến kháng thuốc trên bệnh nhân viêm gan siêu vi B mạn điều trị với thuốc nucleoside/nucleotide, Tạp chí Y học TP. Hồ Chí Minh, 21(1), 15. Google Scholar
[7]
. Nguyễn Minh Ngọc, Bùi Hữu Hoàng (2011), Kiến thức và sự tuân thủ của bệnh nhân người lớn nhiễm virus viêm gan B khám tại Viện Pasteur TP. Hồ Chí Minh, Tạp chí Y học TP. Hồ Chí Minh, 15(1), 291 Google Scholar
[8]
. K O Akande, A O Faneye, B A Olusola, et al (2021). Adherence to Medication among Patients with Chronic Hepatitis B Infection Attending a Tertiary Hospital in South Western Nigeria. West Afr J Med, 38(7), 629-633. Google Scholar
[9]
. Nguyễn Thị Hoài Thương, Lưu Thùy Linh, Nguyễn Mạnh Trường (2023). Đánh giá sự tuân thủ điều trị của bệnh nhân viêm gan virus B mạn tính tại phòng khám viêm gan. Tạp chí Truyền nhiễm Việt Nam, 3(43), 95-100. Google Scholar
[10]
. Đỗ Thị Kim Liên, Nguyễn Thị Lan Anh (2022). Tuân thủ điều trị thuốc kháng vi rút của bệnh nhân viêm gan B mạn tính tại Bệnh viện đa khoa Quốc tế Hải Phòng . Tạp chí nghiên cứu y học, 163(2), 154-163. Google Scholar
[11]
. Xu K, Liu LM, Farazi PA, et al (2018). Adherence and perceived barriers to oral antiviral therapy for chronic hepatitis B. Glob Health Action, 11(1), 1433987, doi: 10.1080/16549716.2018.1433987. Google Scholar
[12]
. Abu-Freha N, Abu Tailakh M, Fich A, et al (2020). Adherence to Anti-Viral Treatment for Chronic Hepatitis B. J Clin Med, 9(6): E1922. doi: 10.3390/jcm9061922. 50 Google Scholar
[13]
. Derya Ozyigitoglu, Dilek Yildiz Sevgi, Ceren Atasoy Tahtasakal et al (2022). Adherence to Treatment with Oral Nucleoside/Nucleotide Analogs in Patients with Chronic Hepatitis B. Sisli Etfal Hastan Tip Bul, 56(4), 543-551, Google Scholar