Articles Vol. 66 No. CĐ3-HNKH Ký Sinh Trùng VN lần thứ 51 24/03/2025

19. Toxocara canis INFECTION AND SERUM TOTAL IgE CONCENTRATION IN PATIENTS WITH URTICARIA AT PASTEUR DA LAT MEDICAL CENTER, LAM DONG

Tran Thi Hue Van1,2, Tran Dinh Hung3,4
1 Ho Chi Minh City University of Medicine and Pharmacy
2 Đại học Y Dược TP Hồ Chí Minh
3 Pasteur Medical Center Dalat, Lam Dong
4 Trung tâm Y khoa Pasteur Đà Lạt, Lâm Đồng
Corresponding author: huevan@ump.edu.vn
DOI: 10.52163/yhc.v66iCĐ3.2139
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Keywords
Urticaria Toxocaca canis infection serum total IgE
Abstract

Background: The zoonotic roundworms Toxocara canis is not only present worldwide in its definitive hosts; it also frequently occur in other animal called paratenic hosts including humans. The relationship between Toxocara species with allergic reactions was reported in the recent century.

Objectives: Our research to detemine the seroprevalance of anti - T. canis antibody, the level of serum total IgE and its association in chronic urticaria patients.

Subject and method: Cross - sectional study of 420  patients taken ELISA method for examining T. canis parasite and serum total IgE at the hospital of Pasteur Da Lat 2 Medical Center, Lam Dong from 01/02/2024 - 01/11/2024. Result: In 420 patients, 38.8% were males and 61.2% were females, all of whom were in Lam Dong province, with serum total IgE > 40 IU/ml accounting for 83.6% and 11.4% of patients with co-allergies. The prevalence of T. canis infection with IgG+ accounted for 33.1%. Serum total IgE were higher in males than in females (236.70 IU/mL versus 193.89 IU/mL), with p < 0.001. Serum total IgE levels of patients with chronic urticaria and T. canis were statistically significantly higher than those of the (p<0.005) chronic urticaria patients. Conclusion: T. canis infection rate is 33,1% and associates with serum total IgE levels of patients with chronic urticaria.

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