Articles Vol. 66 No. CĐ3-HNKH Ký Sinh Trùng VN lần thứ 51 24/03/2025

6. PREVALENCE, SPECIES COMPOSITION AND AZOLE RESISTANCE OF CANDIDA SPP. IN WOMEN VISITING CAN THO CENTRAL GENERAL HOSPITAL

Phan Hoang Dat1,2, Nguyen Le Thi Cam Tu1,2, Dinh Thi Huong Truc2,3, Nguyen Thi Thao Linh2,3, Huynh Si Hung2,3, Truong Phuoc Dang2,3, Bui Chung My Anh2,3, Tran Trang Bao Ngoc2,4, Vo Thanh Tri5,6, Le Chi Dung2,3
1 Can Tho University of Medicine - Pharmacy
2 Trường Đại học Y Dược Cần Thơ
3 Can Tho University of Medicine – Pharmacy
4 Can Tho University of Medicine and Pharmacy
5 HUONG CHAU INTERNATIONAL HOSPITAL
6 Bệnh viện Quốc tế Phương Châu
Corresponding author: phdat@ctump.edu.vn
DOI: 10.52163/yhc.v66iCĐ3.2122
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Keywords
Candida vaginitis culture identification resistance
Abstract

Background: Vaginitis is a common condition in women, and Candida spp. is one of the frequent causes. Currently, the diagnosis and treatment of Candida spp. In Can Tho city and the Mekong Delta still face some difficulties, along with the increasing resistance of Candida spp.

Objective: Determine the prevalence, species composition, and azole resistance rate of Candida spp. isolated from women visiting Can Tho Central General Hospital.

Subject and method: A cross-sectional descriptive study on 160 samples of vaginal discharge from women visiting the Obstetrics and Gynecology clinic at Can Tho Central General Hospital. The vaginal discharge samples were cultured, identified and performed to antifungal susceptibility testing.

Result: The prevalence of vaginal Candidiasis in women visiting the clinic was 35.6%, in which Candida albicans is the most prevalent species (66.7%). The isolated Candida spp. showed resistance to fluconazole, itraconazole, ketoconazole, and voriconazole, with resistance proportion of 21.1%, 45.6%, 10.5%, and 14.0%, respectively.

Conclusion: The prevalence of vaginal Candidiasis in women remains high, and Candida albicans is the primary pathogen. Additionally, these species exhibit a high rate of resistance to fluconazole and itraconazole.

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