Articles Vol. 66 No. 2 04/03/2025

11. EARLY DIAGNOSIS OF HYPOTHYROIDISM AFTER TOTAL THYROIDECTOMY IN PAPILLARY THYROID CANCER PATIENT AT THE NATIONAL ENDOCRINOLOGY HOSPITAL

Do Gia Nam1,2, Do Trung Quan3,4, Nguyen Thi Quynh Mai1,2, Le Huu Thanh1,2
1 National Hospital of Endocrinology
2 Bệnh viện Nội tiết Trung ương
3 Hanoi Medical University
4 Đại học Y Hà Nội
Corresponding author: dogianam@gmail.com
DOI: 10.52163/yhc.v66i2.2081
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Keywords
Hypoparathyroidism papillary thyroid cancer
Abstract

Objective: To describe the early hypoparathyroidism status and some related factors in patients after total thyroidectomy due to papillary thyroid cancer.

Materials and method: A cross-sectional descriptive study on 118 patients with papillary thyroid cancer who underwent total thyroidectomy. The hypoparathyroidism status was assessed within the first 24 hours and after 3 months. Results: The rate of hypoparathyroidism within the first 24 hours after surgery was 16.9%, and at the 3-month mark, it was 3.4%. The risk of early hypoparathyroidism after surgery increased in patients with tumors larger than 20 mm compared to those with tumors ≤ 10 mm (OR=3.4, 95% CI 1.1-10.7; p < 0.05); in the group with capsular invasion compared to the group without capsular invasion (OR=3.7, 95% CI 1.3-10.5; p < 0.05); and in the group undergoing central + lateral neck lymph node dissection compared to those not undergoing lymph node dissection (OR=10, 95% CI 1.2-83.6; p < 0.05).

Conclusion: The rate of hypoparathyroidism within the first 24 hours after total thyroidectomy for papillary thyroid cancer is high, especially in high-risk individuals.

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