Articles Vol. 66 No. 1 07/01/2025

10. THE RESULTS OF THE ASSESSMENT OF INTERVENTIONS IN TREATING DEMENTIA IN THE ELDERLY BY NON-MEDICINAL METHODS COMBINED WITH ORIENTAL MEDICAMENT GINKGO BILOBA IN NGHE AN PROVINCE (2022 - 2023)

Tang Viet Ha1,2, Cao Ba Loi3,4, Duong Dinh Chinh5,6
1 Northwestern Nghe An General Hospital
2 Bệnh viện Đa khoa khu vực Tây Bắc tỉnh Nghệ An
3 National Institute of Malariology, Parasitology and Entomology
4 Viện Sốt rét-Ký sinh trùng-Côn trùng Trung Ương
5 Nghi Loc District Committee, Nghe An Province
6 Huyện uỷ Nghi Lộc tỉnh Nghệ An
Corresponding author: Tangviethabv@gmail.com
DOI: 10.52163/yhc.v66i1.1909
25 Views
15 Downloads
Abstract

Objective: The results of the assessment of interventions in treating dementia in the elderly by non-medical methods combined with oriental medicament Ginkgo Biloba in Nghe An province. (2022-2023)

Method: Research comparing pre-intervention and post-intervention, the uncontrolled intervention research method

Results: Among 125 patients treated with non-drug intervention combined with Ginkgo Biloba herbal medicine, the rate of normal patients increased to 40% after 3 months and 60.8% after 6 months. Patients at mild levels decreased from 63.2% to 40% after 3 months and 26.2% after 6 months. Patients at moderate levels decreased from 30.4% to 16% after 3 months and 11.2% after 6 months. Patients at severe levels decreased from 6.4% to 4% after 3 months and 1.6% after 6 months. The average MMSE point increased from 19.6 ± 3.67, after 3 months of intervention 21.8 ± 3.79, after 6 months of intervention 23.3 ±. The difference was statistically significant (p < 0.001). The average ADL point increased from 4.59 ± 1.34, after 3 months, it increased to 4.87 ± 1.16; after 6 months, it increased to 5.29 ± 0.92, the difference was statistically significant (p < 0.05). The average IADL point increased from 2.38 ± 1.52, after 3 months of intervention, it increased to 3.13 ± 1.75, after 6 months of intervention, it increased to 4.16 ± 1.74, the difference was statistically significant (p < 0.05).

Conclusion: Nonpharmacological interventions for dementia combined with the use of Ginkgo Biloba herbal medicine have shown good results.

References
[1]
Organization World Health (2017), “Global action plan on the public health response to dementia 2017–2025”, pp. . Google Scholar
[2]
Bộ Y tế (2020), “Hướng dẫn chẩn đoán và điều trị một số rối loạn tâm thần thường gặp” Quyết định số 2058/QĐ-BYT ngày 14 tháng 5 năm 2020. Google Scholar
[3]
José María García-Alberca , Esther Gris , Silvia Mendoza (2022), Combined treatment with Ginkgo biloba extract EGb 761 plus acetylcholinesterase inhibitors improved cognitive function and neuropsychiatric symptoms in patients with mild cognitive impairment, 2022 Aug 2;8(1):e12338. doi: 10.1002/trc2.12338. eCollection 2022. . Google Scholar
[4]
Creavin S. T., Wisniewski S., et al. (2016), “Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations”, Cochrane Database Syst Rev, 2016(1), pp. . Google Scholar
[5]
Shelkey, Mary and Wallace, Meredith (2012), “Katz index of independence in activities of daily living Công trình nghiên cứu khoa học (ADL)”, International Journal of Older People Nursing. 2(3), pp. pp.204-212. . Google Scholar
[6]
Lawton,M.P, & Brody, E.M. (1969), Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist, 9, 179-186. Google Scholar
[7]
Nguyễn Bích Ngọc (2014), “Chất lượng cuộc sống của bệnh nhân Alzheimer, người chăm sóc và đánh giá hiệu quả của một số biện pháp can thiệp không dùng thuốc”. Google Scholar
[8]
M. Mazza, A. Capuano, P. Bria, S. Mazza (2006), Ginkgo biloba and donepezil: a comparison in the treatment of Alzheimer’s dementia in a randomized placebo-controlled double-blind study, 156. Google Scholar
[9]
Ihl, R. et al. (2011). Efficacy and safety of a once-daily formulation of Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomized controlled trial. International Journal of Geriatric Psychiatry, 26, 1186–1194. . Google Scholar
[10]
Yu Zheng, , † Yi Xie, , Ming Qi, , Ling Zhang, Wei Wang, Wanrong Zhang, Liju Sha, Jiawen Wu, Wanting Li, and Ting Wu (2021), Ginkgo Biloba Extract Is Comparable With Donepezil in Improving Functional Recovery in Alzheimer’s Disease: Results From a Multilevel Characterized Study Based on Clinical Features and Resting-State Functional Magnetic Resonance Imaging, 2021 Aug 3. doi: 10.3389/fphar.2021.721216. Google Scholar