Articles Vol. 65 No. CĐ 12 - Bệnh viện Thủ Đức 12/12/2024

25. PREVALENCE AND FACTORS RELATED MEDICATION ADHERENCE IN ELDERLY PATIENTS WITH ACUTE CORONARY SYNDROME

Tran Tan Dat1,2, Nguyen Ngoc Quynh Dung1,2
1 University of Health Sciences, Vietnam National University at Ho Chi Minh City
2 Trường Đại học Khoa học Sức khỏe, Đại học Quốc gia Thành phố Hồ Chí Minh
Corresponding author: ttdat@medvnu.edu.vn
DOI: 10.52163/yhc.v65iCD12.1835
31 Views
10 Downloads
Keywords
Acute coronary syndrome in the elderly recommended drug treatment medication adherence
Abstract

Objective: To determine the rate and the factors related to medication adherence in elderly patients with acute coronary syndrome

Research objects and methods: A cross-sectional and longitudinal study was conducted in all patients 60 years of age or older with acute coronary syndrome discharge from the Cardiovascular Center at Thong Nhat hospital from June 2020 to June 2021. Eligible patients receiving guideline-recommended medications were followed up at least 6 months in Outpatients Department

Results: There were 303 patients ≥ 60 years old diagnosed with acute coronary syndrome discharged from the hospital. The prevalence of adherence of 5 classes guideline-recommended drugs was 33.3% at 6 months. Factors related to drug adherence in elderly patients with acute coronary syndrome after multivariate regression analysis included: Older age (> 70 years old), Killip class: II-III-IV and no angioplasty and stent insertion.

Conclusion: The rate of medication adherence after acute coronary syndrome in elderly patients is still low. Factors related to medication adherence in elderly patients with acute coronary syndrome are: 1. Older age (> 70 years old), 2. Killip class: II-III-IV, 3. No angioplasty and stent insertion

References
[1]
Bộ Y Tế. Hướng dẫn chẩn đoán và xử trí hội chứng mạch vành cấp. 2019 Google Scholar
[2]
Collet JP, Thiele H, Barbato E, et al. ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. European Heart Journal. 2020. 42 (14): 1289–1367. Google Scholar
[3]
Nguyen T, Le KK, Cao KTH, et al. Association between in-hospital guideline adherence and postdischarge major adverse outcomes of patients with acute coronary syndrome in Vietnam: a prospective cohort study. BMJ Open, 2017. 7: e017008. Google Scholar
[4]
Nguyễn Thị Thanh Tâm, Nguyễn Văn Lưu, Phạm Thị Thu Hương. Một số yếu tố liên quan đến tuân thủ điều trị của người bệnh sau can thiệp động mạch vành qua da tại tỉnh Hải Dương năm 2018. Khoa học điều dưỡng. 2018. 1 (3): 16 – 21 Google Scholar
[5]
Thygesen K, Alpert SJ, Jaffe SA, et al. Fourth universal definition of myocardial infarction 2018. European Heart Journal. 2019. 40 (3), 237–269 Google Scholar
[6]
Võ Thị Dễ. Nghiên cứu sự tuân thủ điều trị của bệnh nhân bệnh động mạch vành đã được can thiệp Luận án tiến sỹ Y học, Đại học Y dược TPHCM. 2009. Google Scholar
[7]
Hee JB, Yang Y, Choi E J. Optimal medical therapy for secondary prevention after an acute coronary syndrome: 18- month follow-up results at a tertiary teaching hospital in South Korea. Dove Press journal: Therapeutics and Clinical Risk Management. 2016. 12: 167–175 Google Scholar
[8]
Yaman WK, Yahaya H, Noorizan AA, et al. Trends in adherence to secondary prevention medications in post-acute coronary syndrome patients. Pak. J. Pharm. Sci. 2015. 28 (2): 641-646. Google Scholar