Articles Vol. 65 No. Tiếng Anh 12/12/2024

5. A SCOPING REVIEW: COMPARISON OF COAGULATION PARAMETERS RESULTS IN DECEASED AND RECOVERED COVID-19 PATIENTS

Dinh Thi Thu Trang1, Hoang Thi Ngoc Anh1, Nguyen Hoang Long1, Tran Quoc Thang1,2, Dao Van Dung1, Pham Van Thao1, Hoang Van Tuan1,3, Bui Thi Mai An1
1 Phenikaa University
2 Institude of Community Health
3 Phenikaa Univeristy
Corresponding author: anh.hoangthingoc@phenikaa-uni.edu.vn
DOI: 10.52163/yhc.v65i13.1727
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Keywords
coagulation parameters deceased COVID-19 patients recovered COVID-19 patients
Abstract

Objective: Compare coagulation markers between deceased and recovered COVID-19 patients.

Methods: A search of PubMed was conducted to identify peer-reviewed articles published between January 1, 2022, and April 1, 2024. Articles were selected based on predefined inclusion and exclusion criteria. Data extraction focused on coagulation parameters, including platelet count, fibrinogen (Fib), D-Dimer, prothrombin time (PT), and activated partial thromboplastin time (APTT) across six selected studies involving a total of 7,052 patients.

Results: The findings indicated that recovered patients had significantly higher platelet counts compared to deceased patients (p < 0.05). D-Dimer and Fib levels were lower in recovered patients, while PT results were significantly prolonged in deceased individuals (p < 0.05). APTT results showed variability, with some studies reporting higher levels in deceased patients, while others indicated longer APTT in recovered patients, remaining within normal ranges.

Conclusion: Coagulation markers exhibit significant differences between deceased and recovered COVID-19 patients, suggesting their potential utility in predicting disease severity and guiding clinical management.

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