Articles Vol. 65 No. CĐ10 - Bệnh viện Thống Nhất 30/10/2024

31. RESULT OF PULSE CORTICOSTEROID AND PLASMAPHERESIS IN TREATMENT OF RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS IN THE ELDERLY: CASE REPORT

Nguyen Bach1,2, Vu Nguyen Khanh Trang3,4
1 Thong Nhat Hospital
2 Bệnh viện Thống Nhất
3 University of Medicine Pham Ngoc Thach
4 Trường Đại học Y Khoa Phạm Ngọc Thạch
Corresponding author: nguyenbach69@gmail.com
DOI: 10.52163/yhc.v65iCD10.1619
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Keywords
Rapidly progressive glomerulonephritis pauci-immune crescentic glomerulonephritis pulse corticosteroids plasmapheresis
Abstract

Rapidly progressive glomerulonephritis is a rare disease, especially in the elderly, that is a medical emergency in nephrology requiring prompt diagnosis and treatment to rescue the renal function.

Objectives: to evaluate the results of the therapy of pulse corticosteroids and plasmapheresis in a case.

Patients: male, 69 years old. The reason for admission was edema of the lower extremities. The initial diagnosis was nephrotic syndrome – acute kidney injury. Laboratory result confirmed the diagnosis of rapidly progressive glomerulonephritis. The patient was treated with pulse corticosteroids and plasmapheresis.

Method: case report

Results: Renal biopsy was performed to conclude the pauci-immune crescentic glomerulonephritis. The ANCA tests were negative. The kidney function was recovered rapidly after 3 times of plasma exchange and discharged from the hospital after completing 10 courses of plasmapheresis.

Conclusion: Prompt and aggressive treatment with pulse corticosteroids and plasmapheresis attained good results that rescued the patient and kidney function recovered completely.

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