Objective: Assessing the use of proton pump inhibitors (PPI) at 120 Military Hospital in Tien Giang province. Subjects and methods: Cross-sectional descriptive study on 4532 outpatient prescriptions of patients who were prescribed drugs by doctors from July 1 st , 2020 to July 30 th , 2020 at clinics of the examination department - Military Hospital 120. Results: The highest percentage of patients indicated to use proton pump inhibitors was the group of patients in working age from 20 - 60 years old, accounting for 62.16%. The percentage of female patients accounted for much higher than male patients, respectively 62.35% and 37.65%. The most indicated proton pump inhibitors were omeprazole at the rate of 60.06%, followed by Pantoprazole at the rate of 21.89%, proton pump inhibitors with the lowest percentage were Rabeprazole at the rate of 0.88%. For gastroesophageal reflux disease, gastroenteritis prevention, proton pump inhibitors were widely used as omeprazole. The drugs omeprazole, pantoprazole and esomeprazole all had a predominant ratio of 40mg doses. Conclusion: The prevalence of PPIs indicated for use was mainly female, aged 20-60 years old. The most commonly prescribed drug was omeprazole with a dose of 40mg in the most common group of diseases was gastroesophageal reflux disease, prevention of gastroenteritis.
Keywords
Situation of drug use, proton pump inhibitors (PPIs)
Abstract
References
[1]
Bộ Y tế (2006), Tương tác thuốc và chú ý khi chỉ định, NXB Y học.
Google Scholar
[3]
Bộ môn Nội - Đại học Y Dược Huế (2009). Viêm dạ dày, Giáo trình sau đại học Bệnh Tiêu hóa Gan mật:
Google Scholar
[4]
-169.
Google Scholar
[5]
Bùi Mai Nguyệt Ánh (2013). Khảo sát tình hình sử dụng thuốc ức chế bơm proton trong kê đơn thuốc Bảo hiểm
Google Scholar
[6]
y tế ngoại trú tại Bệnh viện đa khoa Thống Nhất Đồng Nai năm 2013.
Google Scholar
[7]
Mai Nguyệt Ánh (2011). So sánh hiệu quả điều trị viêm loét DD-TT do nhiễm HP giữa hai phác đồ PAL và
Google Scholar
[8]
PAC tại bệnh viện ĐK Đồng Nai.
Google Scholar
[9]
Pankaj Jay Pasricha Willemlintje A Hoogerwerf (2005). Pharmacotheraphy of gastric acidity, peptid ulcers and
Google Scholar
[10]
gastroesophageal reflux disease. Goodman & Gilmans The Pharmacological basis of therapeutics.eleventh edition, Mr
Google Scholar
[11]
Graw Hill: 967-982.
Google Scholar
[12]
Ahmed Yacoob Mayet (2007). Improper use of antisecretory drugs in a tertiary care teaching hospital: An
Google Scholar
[13]
observational study. The Saudi Journal of Gastroenterology, 13(3): 124-128.
Google Scholar
[14]
John Del Valle (2009). Zollinger-Ellison syndrome Texbook of Gastroenterology, fifth edition. Wiley
Google Scholar
[15]
Blackwell, 1: 982-988.
Google Scholar
[16]
Mandel KG, Dadgy BP, Brodie DA (2000). Review article alginateraft formoulations in the treatment of
Google Scholar
[17]
heartbum ang acid reflux, Aliment Pharmacol Ther14(6): 669-690.
Google Scholar