Articles Vol. 65 No. CĐ 6 - Bệnh viện Lê Văn Thịnh 31/07/2024

30. EPIDEMIOLOGICAL, CLINICAL FEATURES AND OUTCOMES IN PATIENTS WITH HIV/AIDS ADMITTED TO HOSPITAL FOR TROPICAL DISEASE

Tran Minh Hoang1,2, Ly Quoc Cong3,4, Dang The Hung2,5, Nguyen Van Lil1,2, Le My Duyen1,2, Nguyen Le Nhu Tung6,7
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 Đại học Y Dược TP. Hồ Chí Minh
3 Le Van Thinh Hospital
4 Bệnh viện Lê Văn Thịnh
5 University of Medicine and Pharmacy
6 Hospital for Tropical Diseases
7 Bệnh viện Bệnh Nhiệt Đới
Corresponding author: Dr.hoangtm@gmail.com
DOI: 10.52163/yhc.v65iCD6.1385
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Abstract

Background: Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) continue to be a major global health. Highly-active antiretroviral therapy (HAART) had a dramatic impact on the AIDS epidemic; in particular, it has greatly changed the mortality profile for human immunodeficiency virus (HIV)-infected individuals. As survival increases, so does the likelihood that diseases other than those related to AIDS will incur among HIV-infected individuals.

Objectives: To describe epidemiological, clinical features and outcomes in patients with HIV/ AIDS at the Hospital for Tropical Disease in Ho Chi Minh City.

Methods: Describe a retrospective case series in all patients with HIV/AIDS admitted to Department E, Hospital for Tropical Disease from January 2021 to May 2021.

Results: 203 patients with HIV/AIDS were enrolled in the study. The male/female ratio was 5/1; most patients (56,2%) were aged 31-50, 46,3% patients were malnutrition. 62,3% patients were diagnosed with < 6 months, 74,4% had T CD4+ < 200 cells/mm3. 11,8% patients died. Fever is the most common symtom (57,1%). Diseases did not related to AIDS stage include infections (36,9%), oral candidiasis (19,2%), pulmonary tuberculosis (17,3%). HIV-related opportunistic infections include pneumocystis jirovecii pneumonia (43,2%), extrapulmonary tuberculosis (24%).

Conclusion: The rate of hospitalization due to opportunistic diseases related to HIV/AIDS is still high. Increase hopitalization rates due to illnesses unrelated to HIV/AIDS.

References
[1]
WHO. HIV/AIDS WHO 2021 [Available from: Https://www.who.int/news-room/fact-sheets/detail/hiv-aids. Google Scholar
[2]
Cục phòng chống HIV/AIDS - Bộ Y tế. Báo cáo tổng kết công tác Phòng, chống HIV/AIDS năm 2020. 2021. Google Scholar
[3]
Nhiên NT. Chương trình mục tiêu quốc gia Cổng thông tin Bộ Y tế Bộ Y tế; 2020 [Available from: Https://moh.gov.vn/chuong-trinh-muc-tieuquoc-gia/-/asset_publisher/7ng11fEWgASC/content/viet-nam-la-1-trong-4-quoc-gia-cochat-luong-ieu-tri-hiv-aids-tot-nhat-the-gioi. Google Scholar
[4]
Palella Jr FJ, Delaney KM, Moorman AC et al. Declining morbidity and mortality among patients with advanced human immunodeficiency Google Scholar
[5]
virus infection. New England Journal of Medicine. 1998;338(13):853-60. Google Scholar
[6]
Krishnaratne S, Hensen B, Cordes J et al., Interventions to strengthen the HIV prevention cascade: A systematic review of reviews. Lancet HIV. 2016;3(7):e307-17. Google Scholar
[7]
Costa JO, Ceccato M, Silveira MR et al., Effectiveness of antiretroviral therapy in the single-tablet regimen era. Rev Saude Publica. 2018;52:87. Google Scholar
[8]
Our World in Data. Prevalence, new cases and deaths from HIV/AIDS, World, 1990 to 2017 [Available from: Https://ourworldindata.org/grapher/deaths-and-new-cases-of-hiv?country=~OWID_WRL. Google Scholar
[9]
UNAIDS. Global HIV & AIDS statistics — Fact sheet 2020 [Available from: Https://www.unaids.org/en/resources/fact-sheet. Google Scholar
[10]
UNAIDS. UNAIDS DATA 2021 2021 [Available from: Https://www.unaids.org/en/resources/documents/2021/2021_unaids_data. Google Scholar
[11]
Hoàng TM. Hạ natri máu trên bệnh nhân nhiễm HIV/AIDS. Tạp chí y học thành phố Hồ Chí Minh. 2016;1:312-8. Google Scholar
[12]
Tùng NLN. Đặc điểm dịch tễ, lâm sàng, cận lâm sàng nhiễm trùng huyết trên bệnh nhân người lớn nhiễm HIV/AIDS tại BV Bệnh NHiệt Đới Google Scholar
[13]
TP. Hồ Chí Minh. Luận văn tốt nghiệp Bác sĩ Nội trú chuyên ngành Nhiễm, Đại học Y Dược thành phố Hồ Chí Minh. 2006. Google Scholar
[14]
Boniphace I, Omari M, Susan Fred R, Ferdinand M, Marcel T. HIV/AIDS Clinical Manifestations and their Implication for Patient Clinical Staging in Resource Limited Settings in Tanzania. Open AIDS J. 2011;5:9-16. Google Scholar
[15]
Grinsztejn B, Luz PM, Pacheco AG, Santos DV, Velasque L, Moreira RI, et al. Changing mortality profile among HIV-infected patients in Rio Google Scholar
[16]
de Janeiro, Brazil: Shifting from AIDS to nonAIDS related conditions in the HAART era. PLoS One. 2013;8(4):e59768. Google Scholar
[17]
Hasse B, Bernasconi E, Furrer H, Eyer MM, Kovari H. [HIV-associated non-AIDS conditions]. Ther Umsch. 2014;71(8):483-9. Google Scholar