Articles Vol. 65 No. CĐ 4 - Hội Y học Giới tính Việt Nam 30/05/2024

15. SEXUAL DYSFUNCTION IN KLINEFELTER'S SYNDROME PATIENTS IN ANDROLOGY AND FERTILITY HOSPITAL OF HANOI IN 2023-2024

Dinh Huu Viet1,2, Nguyen Van Kien1,2, Nguyen Thi Huyen Trang1,2, Trinh Kien Cuong1,2, Pham Minh Ngoc1,2, Pham Thi My Hanh1,2
1 Andrology and Fertility Hospital of Hanoi
2 Bệnh viện Nam học và Hiếm muộn Hà Nội
Corresponding author: vietdh@afhanoi.com
DOI: 10.52163/yhc.v65iCD4.1164
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Abstract

 Objective: To evaluate of sexual activity and function in Klinefelter’s syndrome patients in Andrology and Fertility Hospital of Hanoi and some related factors in 2023-2024.

Methods: A cross-sectional study was conducted on 70 males with Klinefelter syndrome in the Andrology and Fertility Hospital of Hanoi Janury 2023 to March 2024. Evaluating erectile dysfunction through the scale (IIEF-5), premature ejaculation diagnostic tool (PEDT), intravaginal ejaculation latency time (IELT).

Results: The mean age patients were 32.6 ± 4.2 years. The rate of erectile dysfunction was 22.9%, the IIEF-5 erectile dysfunction score was 23.21 ± 1.95. The rate of erectile dysfunction was higher in patients over 30 years old and in patients with overweight and obesity, p < 0,05. The rate of premature ejaculation was 31.4%, the average waiting time for ejaculation in the vagina was 6.97 ± 6.02 minutes, the shortest was 1 minute, the longest was 30 minutes. PEDT premature ejaculation score was 7.71 ± 2.56 points.

Conclusion: The rate of erectile dysfunction and premature ejaculation in the KS group seem to be comparable with the data of the general population. Two contributing factors to elevated risk of erectile dysfunction are older age group (over 30 years old), overweight and obesity. Hopefully, there will be more research evaluating sexual function in KS men, contributing to creating a comprehensive basis for consultation and treatment, enhancing the quality of life for Klinefelter patients.

References
[1]
Gary B , Umasuthan S, Jennie F et al., Klinefelter Google Scholar
[2]
syndrome: going beyond the diagnosis. Archives Google Scholar
[3]
of disease in childhood, 2023. 108(3): p. 166- Google Scholar
[4]
Longhi EV et al., Klinefelter: Which Sexuality. Google Scholar
[5]
Journal of Sexual Medicine Research, 2023. 120: Google Scholar
[6]
[7]
RC Rosen, JC Cappelleri, MD Smith et al., Google Scholar
[8]
Development and evaluation of an abridged, Google Scholar
[9]
-item version of the International Index of Google Scholar
[10]
Erectile Function (IIEF-5) as a diagnostic tool Google Scholar
[11]
for erectile dysfunction. International Journal of Google Scholar
[12]
Impotence Research, 1999. 11(6): p. 319-326. Google Scholar
[13]
Nguyễn Hoài Bắc, Nguyễn Cao Thắng, Chuẩn Google Scholar
[14]
hóa bộ câu hỏi iief-5 tiếng Việt và ứng dụng Google Scholar
[15]
trong chẩn đoán rối loạn cương dương. Tạp chí Google Scholar
[16]
Nghiên cứu Y học, 2022, 152(4): p. 86-94. Google Scholar
[17]
Tara S, Michael AP, Stanley A et al., Google Scholar
[18]
Development and validation of a premature Google Scholar
[19]
ejaculation diagnostic tool. European Urology, Google Scholar
[20]
52(2): p. 565-573. Google Scholar
[21]
H Okada, H Fujioka, N Tatsumi et al., Google Scholar
[22]
Klinefelter’s syndrome in the male infertility Google Scholar
[23]
clinic. Human Reproduction, 1999. 14(4): p. Google Scholar
[24]
[25]
G Corona, L Petrone, F Paggi et al., Sexual Google Scholar
[26]
dysfunction in subjects with Klinefelter’s Google Scholar
[27]
syndrome. International journal of Andrology, Google Scholar
[28]
33(4): p. 574-580. Google Scholar
[29]
Vogt, H.-J., Sexual behavior in Klinefelter’s Google Scholar
[30]
syndrome. Springer. p. 163-169, 1984. Google Scholar
[31]
A Yoshida , K Miura, K Nagao et al., Sexual Google Scholar
[32]
function and clinical features of patients with Google Scholar
[33]
Klinefelter’s syndrome with the chief complaint Google Scholar
[34]
of male infertility. International journal of Google Scholar
[35]
andrology, 1997. 20(2): p. 80-85. Google Scholar
[36]
Nieschlag E et al., Disorders at the testicular Google Scholar
[37]
level. Andrology: male reproductive health Google Scholar
[38]
dysfunction, 2010: p. 193-238. Google Scholar
[39]
A Ferlin, R Selice, S Angelini et al., Endocrine Google Scholar
[40]
and psychological aspects of sexual dysfunction Google Scholar
[41]
in Klinefelter patients. Andrology, 2018. 6(3): p. Google Scholar
[42]
[43]
H El Bardisi, A Majzoub, S Al Said et al., Sexual Google Scholar
[44]
dysfunction in Klinefelter’s syndrome patients. Google Scholar
[45]
Andrologia, 2017. 49(6): p. e12670. Google Scholar
[46]
Duterte E, T Segraves, S Althof, Google Scholar
[47]
Psychotherapy and pharmacotherapy for Google Scholar
[48]
sexual dysfunctions. 2007. DOI:10.1093/ Google Scholar
[49]
med:psych/9780195304145.003.0019 Google Scholar
[50]
Leslie S, T Sooriyamoorthy, Erectile Google Scholar
[51]
Dysfunction. StatPearls, 2024. Google Scholar