Articles Vol. 65 No. CĐ 3 - Bệnh viện Phổi Trung ương 15/05/2024

26. CLINICAL FEATURES AND RISK FACTORS OF PATIENTS WITH INVASIVE PULMONARY ASPERGILLOSIS AT NATIONAL LUNG HOSPITAL FROM 2019 TO 2020

Khuat Thi Luong1,2, Nguyen Thi Bich Ngoc1,2, Mai Manh Tu1,2
1 National Lung Hospital
2 Bệnh viện Phổi Trung ương
Corresponding author: Luongkhuat.dr@gmail.com
DOI: 10.52163/yhc.v65iCD3.1122
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Keywords
Aspergillus pulmonary, invasive Aspergillosis, clinical, risk factors.
Abstract

Objective: To describe the clinical features and risk factors of patients with invasive pulmonary Aspergillosis treated at the National Lung Hospital.

Methods: Retrospective descriptive study on 47 patients with invasive pulmonary Aspergillosis, treated at the National Lung Hospital from January 2019 to December 2020.

Results: The average age was 54 ± 14 years old, 59.6% were 18-60 years olds, male/female was 2/1. The most common reasons for being hospitalized are breathless (48.9%) and fever (17%). However, the earliest symptoms of the disease appear 1-3 weeks before admission: Fever (40.4%) and phlegm cough (40.4%). 30/47 (63.8%) patients had host factors for EORTC/ MSG, mainly hematological malignancies (34%) and long-term corticosteroid use (23.4%). Other co-morbidities are diabetes (34%), hypertension (10.6%), and chronic hepatitis (14.9%).

Conclusion: Clinical features of invasive pulmonary Aspergillosis are multiform and non-specific, you have to think about fungal infection in patients with risk factors and have persistent respiratory symptoms that do not improve with common treatment.

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