Articles Vol. 65 No. CĐ 3 - Bệnh viện Phổi Trung ương 15/05/2024

12. FACTORS AFFECTING THE RESULT OF TUBERCULOSIS TREATMENT AMONG CHILDREN ADMITTED TO PEDIATRIC DEPARTMENT OF NATIONAL LUNG HOSPITAL FROM 2017 TO 2020

Nguyen Thi Hang1,2, Dinh Ngoc Sy3,4, Hoang Thanh Van1,2
1 National Lung Hospital
2 Bệnh viện Phổi Trung ương
3 Vietnam Medical Association
4 Tổng hội Y học Việt Nam
Corresponding author: Hangnhi16382@gmail.com
DOI: 10.52163/yhc.v65iCD3.1108
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Keywords
Childhood tuberculosis; treatment of paediatric tuberculosis; results of tuberculosis treatment in children; pediatric tuberculosis.
Abstract

Objective: To identify factors affecting the results of treatment of tuberculosis in children at the Department of Pediatrics - National Lung Hospital.

Research method: Prospective descriptive study.

Results: The results of tuberculosis treatment among 320 pediatric patients at the Department of Pediatrics - National Lung Hospital showed that: The successful treatment rate (cured and completed treatment) was 95.9%; the dropped-out rate was 1.9% treatment; the death rate was 2.2%; the prolonging treatment time was 11.6%; the sequelae were 7.5%; the readmission rate during outpatient treatment was 35.3%. There was no difference in treatment success rates according to bacteriological evidence; the pulmonary and extrapulmonary tuberculosis; and the age group. The treatment success rate was lower in the multi-organ TB group and the group whose disease was detected later than 2 months. The mortality rate was higher in the multi-organ TB group (3 organs: 27.3%); and the illness duration of more than 2 months (11.7%). Treatment drop out was most common in children less than 5 years old (2.6%). The proportion of pediatric patients with prolonged treatment was higher in the pulmonary tuberculosis group (15.2%); in the groups of less than 5 years old and group from 10-15 years old (13.5% and 13.8% respectively); and in the TB diagnosis group with bacterial evidence (18.5%). The readmission rate was higher in the group of less than 5 years old (48.4%) and Tuberculosis in 3 organs (81.8%); and Tuberculosis in 4 organs (33.3%). The sequelae occurred mainly in extrapulmonary tuberculosis (16.5%) and 3-organ tuberculosis (9.1%).

Conclusion: The results of tuberculosis treatment in children were related to age, bacteriological evidence, type of tuberculosis, number of organs affected by tuberculosis and time of disease detection.

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