Articles Vol. 65 No. 3 06/05/2024

18. DIAGNOSTIC VALUE OF BLUE LASER IMAGING ENDOSCOPY SYSTEM FOR THE EARLY GASTRIC CANCER AT THE GASTROENTEROLOGY AND HEPATOLOGY CENTER, BACH MAI HOSPITAL

Luong Ngoc Duy1,2, Vu Manh Ha1,2, Le Phu Tai1,2, Nguyen Van Hieu1,2, Ha Phuong3,4, Nguyen Thi Van Hong1,2, Nguyen Tan Dung5,6, Nguyen Cong Long7,8,9,10
1 Bach Mai Hospital
2 Bệnh viện Bạch Mai
3 Hai Duong Provincial General Hospital
4 Bệnh viện Đa khoa tỉnh Hải Dương
5 SHI Cosmetic Dermatology Clinic
6 Phòng Khám Da liễu thẩm mỹ SHI
7 Bach Mai Hospital;
8 University of Medicine and Pharmacy, Hanoi National University
9 Bệnh viện Bạch Mai;
10 Đại học Y Dược, Đại học Quốc Gia Hà Nội
Corresponding author: manhhabmh@gmail.com
DOI: 10.52163/yhc.v65i3.1069
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Abstract

Objective: To evaluate the diagnostic value of magnified BLI endoscopy in early gastric cancer patients at the Gastroenterology and Hepatology Center - Bach Mai Hospital.

Subjects and Methods: A cross-sectional study was conducted on 40 patients with dysplastic lesions in the stomach who underwent endoscopic examination with magnified BLI and histopathology. All patients were evaluated for general characteristics, medical history, clinical symptoms, blood tests, endoscopic imaging, and histopathology.

Results: Lesions were most found in the fundus (72.5%). Dysplastic lesions often had well-defined borders (100%), 66.7% showed abnormal surface pit patterns, and 73.3% exhibited abnormal microvascular structures. The diagnostic sensitivity and specificity of abnormal surface pit patterns were 66.7% and 56%, respectively, with an accuracy of 60%. The diagnostic sensitivity and specificity of abnormal microvascular structures were 73.3% and 60%, respectively, with an accuracy of 65%. Multivariate regression analysis showed a statistically significant correlation between abnormal surface pit patterns, abnormal microvascular structures, and the presence of dysplasia and early gastric cancer. Most patients feel anxious and have a reduced quality of life.

Conclusion: Magnified BLI endoscopy is valuable for diagnosing high-grade dysplastic lesions and early gastric cancer.

References
[1]
Bi Y, Min M, Zhang F et al., The characteristics Google Scholar
[2]
of blue laser imaging and the application Google Scholar
[3]
in diagnosis of early digestive tract cancer. Google Scholar
[4]
Technology in Cancer Research & Treatment. Google Scholar
[5]
;18:1533033819825877.146 Google Scholar
[6]
Togashi K, Nemoto D, Utano K et al., Blue Google Scholar
[7]
laser imaging endoscopy system for the early Google Scholar
[8]
detection and characterization of colorectal Google Scholar
[9]
lesions: a guide for the endoscopist. Therapeutic Google Scholar
[10]
advances in gastroenterology. 2016; 9(1):50-56. Google Scholar
[11]
Thái Văn Dũng, Nguyễn Cảnh Bình, Thái Google Scholar
[12]
Doãn Kỳ và cs, Đánh giá kết quả bước đầu điều Google Scholar
[13]
trị tổn thương loạn sản và ung thư dạ dày sớm Google Scholar
[14]
bằng phương pháp cắt tách hạ niêm mạc qua nội Google Scholar
[15]
soi; Tạp chí Y học Việt Nam,520(1A), 2022. Google Scholar
[16]
doi:10.51298/vmj.v520i1.3760. Google Scholar
[17]
Yao K, The endoscopic diagnosis of early gastric Google Scholar
[18]
cancer. Ann Gastroenterol. 2013;26(1):11-22. Google Scholar
[19]
Published 2013/01/01. Google Scholar
[20]
Cho S-J, Choi I, Kim C et al., Risk of high-grade Google Scholar
[21]
dysplasia or carcinoma in gastric biopsy-proven Google Scholar
[22]
low-grade dysplasia: an analysis using the Vienna Google Scholar
[23]
classification. Endoscopy. 2011:465-471. Google Scholar
[24]
Kim MK, Jang JY, Kim J-W et al., Is lesion Google Scholar
[25]
size an independent indication for endoscopic Google Scholar
[26]
resection of biopsy-proven low-grade gastric Google Scholar
[27]
dysplasia? Digestive diseases and sciences. Google Scholar
[28]
;59:428-435. Google Scholar
[29]
Zhenming Y, Lei S, Diagnostic value of blue laser Google Scholar
[30]
imaging combined with magnifying endoscopy Google Scholar
[31]
for precancerous and early gastric cancer lesions. Google Scholar
[32]
The Turkish Journal of Gastroenterology; 2019; Google Scholar
[33]